yvfR
168
similar to [wiki|ABC transporter] ([metabolite|ATP]-binding protein)
locus
BSU_34090
Molecular weight
33.63 kDa
pI
6.17
function
unknown
product
[wiki|ABC transporter] ([metabolite|ATP]-binding protein)
essential
no
synonyms
yvfR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1131 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,498,352 → 3,499,257
The protein
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transporter domain] (aa 6-230) (according to UniProt)
Structure
[PDB|4YER] (from Thermotoga maritima, 32% identity)
[AF|O07016]
[wiki|Localization]
plasma membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|B6BBB827CB475423FC9A781058141B7D05C4D284|yvfR]-[gene|72E387D5D44FA20D6EEFF1B39B6C9F322F966FC5|yvfS]
description
[Pubmed|26647299]
regulatory mechanism
[protein|F08BE4ACC0ECE1416B012CA72B027423D4D9B00A|desR]: transcription activation, [protein|search|DesR] activates transcription in the non-phosphorylated state at 37°C [pubmed|39344851], in [regulon|protein:F08BE4ACC0ECE1416B012CA72B027423D4D9B00A|desR regulon]
[protein|5BB2B90D5DDD50DD9B4EF9E69925FCBFA642222B|yvfU]: transcription activation, [pubmed|39344851], in [regulon|protein:5BB2B90D5DDD50DD9B4EF9E69925FCBFA642222B|yvfU regulon]
Biological materials
Mutant
MGNA-A481 (yvfR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/481 NBRP B. subtilis, Japan]
BKE34090 (Δ[gene|B6BBB827CB475423FC9A781058141B7D05C4D284|yvfR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE34090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACATGAGCACCTCCTGATC, downstream forward: _UP4_GACGGCAACAGGGAGGCGAT
BKK34090 (Δ[gene|B6BBB827CB475423FC9A781058141B7D05C4D284|yvfR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK34090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACATGAGCACCTCCTGATC, downstream forward: _UP4_GACGGCAACAGGGAGGCGAT
References
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Time of last update: 2024-12-21 22:47:07
Author of last update: Jstuelk