glgC
168
glucose-1-phosphate adenylyltransferase
locus
BSU_30970
Molecular weight
42.44 kDa
pI
4.86
function
glycogen biosynthesis
product
glucose-1-phosphate adenylyltransferase
essential
no
ec
2.7.7.27
synonyms
glgC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0448 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,168,624 → 3,169,766
The protein
Catalyzed reaction/ biological activity
α-D-glucose 1-phosphate + ATP + H+ --> ADP-α-D-glucose + diphosphate (according to UniProt)
Protein family
bacterial/plant glucose-1-phosphate adenylyltransferase family (with [protein|63A4FD35A2E72C665BFA3F2632F06C7A0C954087|glgD], according to UniProt)
Structure
[PDB|5L6S] (E. coli ADP-glucose pyrophosphorylase, 41% identity) [pubmed|27545622]
[AF|P39122]
Paralogous protein(s)
[protein|63A4FD35A2E72C665BFA3F2632F06C7A0C954087|glgD]
Expression and Regulation
Operons
genes
[gene|52C8DE3C78B680C8883D1CD559CBC2D9ABFCC400|glgB]-[gene|B665735B76462724A3C7A1E89D3E613C18F21399|glgC]-[gene|63A4FD35A2E72C665BFA3F2632F06C7A0C954087|glgD]-[gene|EBEA85AD543B79C321CB5F28D1B7E1248640DC1D|glgA]-[gene|3AB4513126EFF54996A54CB7DEB6062C1A06AAC3|glgP]
description
[Pubmed|8145641]
regulation
expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|8145641]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|8145641], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
BKE30970 (Δ[gene|B665735B76462724A3C7A1E89D3E613C18F21399|glgC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GAGCATGGCTACACATTGTT, downstream forward: _UP4_TAATTACTGAAGAGGGGGCA
BKK30970 (Δ[gene|B665735B76462724A3C7A1E89D3E613C18F21399|glgC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GAGCATGGCTACACATTGTT, downstream forward: _UP4_TAATTACTGAAGAGGGGGCA
References
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Time of last update: 2024-12-22 01:46:51
Author of last update: Melvin.boenninger