rplM

rplM
168

ribosomal protein uL13

locus
BSU_01490
Molecular weight
16.15 kDa
pI
10.18
Protein length
Gene length
function
translation
product
ribosomal protein L13 (uL13)
essential
yes
synonyms
rplM

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0102 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
153,842 → 154,279
Phenotypes of a mutant
essential [Pubmed|23002217,12682299]
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The protein
Protein family
universal [wiki|ribosomal protein] uL13 family (single member, according to UniProt)
Structure
[PDB|3J9W] (the [wiki|ribosome]) [Pubmed|25903689]
[AF|P70974]
Expression and Regulation
Operons
genes
[gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]
description
[pubmed|22383849]
regulation
[protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|rel] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
likely autorepression of [gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI] expression upon binding of excess [protein|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM] to the untranslated region of the [gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI] mRNA [Pubmed|17616982]
regulatory mechanism
stringent response: negative regulation, [pubmed|11948165], in [regulon|other_regulator:stringent response|stringent response]
Open in new tab

[gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]->[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]

2024-07-10 01:06:04

Jstuelk

64

1e953db547b59dcb7f45eec2da4084ab9a6fe4e8

7A67E30BD15613891F4B98B693A6AEB3A9872BEF

genes
[gene|84334531D66BE7524021C4B40C3FA05AAFE0D7A6|truA]-[gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]
description
[pubmed|22383849]
regulation
[protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|rel] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
expression is reduced in motile cells as compared to non-motile cells [pubmed|33782055]
regulatory mechanism
stringent response: negative regulation, [Pubmed|11948165], in [regulon|other_regulator:stringent response|stringent response]
Open in new tab

[gene|84334531D66BE7524021C4B40C3FA05AAFE0D7A6|truA]->[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]

2024-07-10 14:25:58

Jstuelk

78

9378802F22213CCB249C12ED6C7E38294E94AEBA

BCBF9D5540A2F40C69EB9BD2FDE789D8B342DBAE

References
36815589,19653700,11948165,10781545,20830302,23002217,25903689,17616982,33782055

B495FFC63413D518138F8C2F3FBC894038C97E0E

Page visits: 4456

Time of last update: 2024-07-15 01:43:21

Author of last update: Jstuelk