rplM

rplM
168

ribosomal protein uL13

locus
BSU_01490
Molecular weight
16.15 kDa
pI
10.18
Protein length
145 aaSequenceBlast
Gene length
438 bpSequenceBlast
function
translation
product
ribosomal protein L13 (uL13)
essential
yes
synonyms
rplM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0102 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
153,842 → 154,279
Phenotypes of a mutant
essential [Pubmed|23002217,12682299]
The protein
Protein family
universal [wiki|ribosomal protein] uL13 family (single member, according to UniProt)
Structure
[PDB|3J9W] (the [wiki|ribosome]) [Pubmed|25903689]
[AF|P70974]
Expression and Regulation
Operons
genes
[gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]
description
[pubmed|22383849]
regulation
[protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|rel] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
likely autorepression of [gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI] expression upon binding of excess [protein|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM] to the untranslated region of the [gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI] mRNA [Pubmed|17616982]
regulatory mechanism
stringent response: negative regulation, [pubmed|11948165], in [regulon|other_regulator:stringent response|stringent response]
Open in new tab

[gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]->[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]

2025-01-15 02:30:20

Jstuelk

85

1e953db547b59dcb7f45eec2da4084ab9a6fe4e8

7A67E30BD15613891F4B98B693A6AEB3A9872BEF

genes
[gene|84334531D66BE7524021C4B40C3FA05AAFE0D7A6|truA]-[gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]
description
[pubmed|22383849]
regulation
[protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|rel] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
expression is reduced in motile cells as compared to non-motile cells [pubmed|33782055]
regulatory mechanism
stringent response: negative regulation, [Pubmed|11948165], in [regulon|other_regulator:stringent response|stringent response]
Open in new tab

[gene|84334531D66BE7524021C4B40C3FA05AAFE0D7A6|truA]->[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]

2025-01-14 18:12:43

Jstuelk

97

9378802F22213CCB249C12ED6C7E38294E94AEBA

BCBF9D5540A2F40C69EB9BD2FDE789D8B342DBAE

References
36815589,19653700,11948165,10781545,20830302,23002217,25903689,17616982,33782055

B495FFC63413D518138F8C2F3FBC894038C97E0E

Page visits: 4785

Time of last update: 2025-01-14 22:09:21

Author of last update: Jstuelk