hbuT

hbuT
168

sporulation protein, transporter for 3-hydroxybutyrate

locus
BSU_39000
Molecular weight
49.98 kDa
pI
8.9
Protein length
Gene length
function
3-hydroxybutyrate utilization
product
transporter for 3-hydroxybutyrate
essential
no
synonyms
hbuT, yxjC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2610 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,002,716 → 4,004,134
Phenotypes of a mutant
reduced uptake of 3-hydroxybutyrate during [wiki|sporulation] [Pubmed|26363016]
The protein
Catalyzed reaction/ biological activity
uptake of 3-hydroxybutyrate [Pubmed|26363016]
Protein family
[wiki|CitM transporter family (TC 2.A.11)] (according to UniProt)
Structure
[AF|P42314]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|B416BB368A96926526458B2258BF8AB928D7C15E|hbuT]-[gene|A7E61C3D12BBDDD3EFD65B1EDBE280497D7B6CD0|scoA]-[gene|7F46EDA8F1EB8D9817C62D7D361FF32F9CD814AD|scoB]-[gene|B7B1D28E50244704324920E5A6F110DA8D63F6C0|yxjF]
description
[Pubmed|10746760]
regulation
expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|12662922]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|12850135,10666464], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|12662922], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
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[gene|B416BB368A96926526458B2258BF8AB928D7C15E|hbuT]→[gene|B7B1D28E50244704324920E5A6F110DA8D63F6C0|yxjF]

2024-10-11 07:36:44

ghost

81

49dda0fadfba300315a7543307ab331d78e27e4b

9C2F2DF9D8BDF9896BE318E36ACFA3F55755DB86

Biological materials
Mutant
MGNA-B727 (yxjC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1726 NBRP B. subtilis, Japan]
BKE39000 (Δ[gene|B416BB368A96926526458B2258BF8AB928D7C15E|hbuT]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE39000 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACACACACATCCCCCGTTT,  downstream forward: _UP4_TAGAAGAAAACGAAAGGGGC
BKK39000 (Δ[gene|B416BB368A96926526458B2258BF8AB928D7C15E|hbuT]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK39000 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACACACACATCCCCCGTTT,  downstream forward: _UP4_TAGAAGAAAACGAAAGGGGC
References
16672620,10746760,12662922,12850135,10666464,26363016

B416BB368A96926526458B2258BF8AB928D7C15E

Page visits: 4164

Time of last update: 2024-10-12 15:04:52

Author of last update: Jstuelk