cccA

cccA
168

cytochrome c550

locus
BSU_25190
Molecular weight
12.63 kDa
pI
5.28
Protein length
Gene length
function
respiration
product
cytochrome c550
essential
no
synonyms
cccA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2010 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,599,523 → 2,599,885
The protein
[wiki|Domains]
transmembrane domain at the N-terminus (aa 5 -25) [Pubmed|2166045]
[wiki|Cofactors]
heme c  [Pubmed|2166045]
Structure
[AF|P24469]
[wiki|Localization]
cell membrane (outer side) [Pubmed|2166045]
Expression and Regulation
Operons
genes
[gene|B3EBB417FB2DE3CE6BAFB910E1913785C162EABF|cccA]
description
[Pubmed|22383849]
regulation
carbon catabolite repression ([protein|search|CcpA]) [Pubmed|22900538,11361075,12850135]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, cre site overlaps -35 region of the promoter [Pubmed|11361075], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|11361075], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
additional information
the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
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[gene|B3EBB417FB2DE3CE6BAFB910E1913785C162EABF|cccA]

2024-11-09 14:40:20

ghost

54

5bfcb42f037b774072923b7b913a7dfce51639e6

54C774AD88F175DF165DAD621649ECFCDB1D47D7

Biological materials
Mutant
BKE25190 (Δ[gene|B3EBB417FB2DE3CE6BAFB910E1913785C162EABF|cccA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE25190 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCCCTTCCCCCTTTTT,  downstream forward: _UP4_TAAAAGAACTATTTTTCTCT
BKK25190 (Δ[gene|B3EBB417FB2DE3CE6BAFB910E1913785C162EABF|cccA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK25190 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCCCTTCCCCCTTTTT,  downstream forward: _UP4_TAAAAGAACTATTTTTCTCT
References
Reviews
33705278
Original Publications
2171986,10024472,12884008,8383048,2166045,12850135,11361075,22900538,22900538,22383849,20817675,10473570,27503613,36422766

B3EBB417FB2DE3CE6BAFB910E1913785C162EABF

Page visits: 3043

Time of last update: 2024-11-10 21:35:09

Author of last update: Jstuelk