arsR

arsR
168

transcriptional regulator of the [wiki|ArsR family], arsenic resistance operon repressor

locus
BSU_25810
Molecular weight
12.15 kDa
pI
4.88
Protein length
Gene length
function
regulation of As (III) efflux
product
transcription repressor ([wiki|ArsR family])
essential
no
synonyms
arsR, yqcJ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0640 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,657,317 → 2,657,634
The protein
Protein family
[wiki|ArsR family]
[wiki|Domains]
[wiki|HTH arsR-type domain] (aa 4-99) (according to UniProt)
Structure
[PDB|1U2W] (CadC from Staphylococcus aureus, 36% identity) [pubmed|15937183]
[AF|P45949]
Expression and Regulation
Operons
genes
[gene|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|arsR]-[gene|74B1AF103E6B236609CD184A1A409A9A04857181|yqcK]-[gene|B749D54249A28A471EF796903A34622A16D5B0BB|arsB]-[gene|DB3527FB78D0B7C144D1699D665788184F19AFE0|arsC]
description
[Pubmed|9537360]
regulation
expressed early during sporulation in the forespore ([protein|search|SigF]) [Pubmed|16497325]
regulatory mechanism
[protein|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|arsR]: repression, [Pubmed|9537360], in [regulon|protein:B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|arsR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|9537360], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|16497325], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
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[gene|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|arsR]→[gene|DB3527FB78D0B7C144D1699D665788184F19AFE0|arsC]

2024-10-04 11:27:43

ghost

65

7d91428def687f36edd853c2144ba36ad881df9d

CB498A4267C57A4A9612EB861EB870A4C106D7B1

Biological materials
Mutant
BKE25810 (Δ[gene|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|arsR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE25810 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCATATCGCCTTCTTTA,  downstream forward: _UP4_TAAAAAAATTTTTTAGGTAT
BKK25810 (Δ[gene|B3D88B9C89154B77D77FB833CA16FD4F4E29FE96|arsR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK25810 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCATATCGCCTTCTTTA,  downstream forward: _UP4_TAAAAAAATTTTTTAGGTAT
References
15948947,9537360,16497325,15937183

B3D88B9C89154B77D77FB833CA16FD4F4E29FE96

Page visits: 7089

Time of last update: 2024-10-10 03:38:19

Author of last update: Melvin.boenninger