cotZ
168
spore crust anchor protein, necessary for the assembly of the spore crust, the outermost layer of the spore coat
locus
BSU_11740
Molecular weight
16.00 kDa
pI
5
function
spore crust assembly
product
spore crust anchor protein
essential
no
synonyms
cotZ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5888 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,249,442 → 1,249,888
Phenotypes of a mutant
mis-assembly of the spore crust [Pubmed|22171814]
The protein
Catalyzed reaction/ biological activity
required for the localization of most crust proteins [pubmed|30582883]
Structure
[AF|Q08312]
Paralogous protein(s)
[protein|B2636947990A303C43CEA8BFBE38811DD233A0A6|cotY]
[wiki|Localization]
outermost layer of the spore coat (crust), localization depends on [protein|825AD8D4315A85CD384F9AF6AD894E38E57C88F7|cotE] [Pubmed|22171814]
more abundant at the mother cell-proximal pole of the forespore [Pubmed|19933362,21665972]
Expression and Regulation
Operons
genes
[gene|B2636947990A303C43CEA8BFBE38811DD233A0A6|cotY]-[gene|B3BA3A44C3EE2747FB594BD7199864E9ECA953CB|cotZ]
description
[Pubmed|7519271]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|7519271,15699190]
regulatory mechanism
[protein|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]: activation, [Pubmed|15621419], in [regulon|protein:0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR regulon]
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|7519271], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|7519271,15699190], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|26577401,15383836], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
BKE11740 (Δ[gene|B3BA3A44C3EE2747FB594BD7199864E9ECA953CB|cotZ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE11740 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTATCCCTCCTGCCTT, downstream forward: _UP4_TAATCATAAGCTGGAAAAGC
BKK11740 (Δ[gene|B3BA3A44C3EE2747FB594BD7199864E9ECA953CB|cotZ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK11740 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTATCCCTCCTGCCTT, downstream forward: _UP4_TAATCATAAGCTGGAAAAGC
References
Reviews
Original Publications
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Time of last update: 2024-12-30 10:40:28
Author of last update: Jstuelk