rbfA
168
ribosome-binding factor A
locus
BSU_16650
Molecular weight
13.25 kDa
pI
9.34
function
translation
product
ribosome-binding factor A
essential
no
synonyms
rbfA, ymxE, ylxO
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0858 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,736,451 → 1,736,804
The protein
Protein family
rbfA family (single member, according to UniProt)
Structure
[PDB|1JOS] (from ''Haemophilus influenzae'', 45% identity)
[AF|P32731]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|9F6C447900410BF64409E5C41A11C76968DADAFA|ylxS]-[gene|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|nusA]-[gene|F4097349A563503468A2A14F062AEAC532C7917A|rnpM]-[gene|7BFA65857F69855DBB3BB64D93B4ED2F09DC705B|rplGA]-[gene|378B77412D0DEA220A97DEC246410509D9B74D46|infB]-[gene|24835CE6CD2E1F183DB9121F29A63101718B5DF9|ylxP]-[gene|B3119A40393A288EF34FC3E9839B6E40AC6A6EA0|rbfA]
description
[Pubmed|8491709]
regulation
autoregulation [wiki|NusA] [pubmed|27571753]
induced by glucose [pubmed|30355672]
expression is reduced in motile cells as compared to non-motile cells [pubmed|33782055]
regulatory mechanism
stringent response: negative regulation, in [regulon|other_regulator:stringent response|stringent response]
[protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|nusA]: attenuation, [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|nusA] stimulates termination [Pubmed|27571753], in [regulon|protein:8887ADC77C43F21CD375BDAA4D38E940786DAD4F|nusA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8491709], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528,26577401], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
BKE16650 (Δ[gene|B3119A40393A288EF34FC3E9839B6E40AC6A6EA0|rbfA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE16650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACTCAATTCAATCACCT, downstream forward: _UP4_TAAAAAAAGAGAGGATAGGC
BKK16650 (Δ[gene|B3119A40393A288EF34FC3E9839B6E40AC6A6EA0|rbfA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK16650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACTCAATTCAATCACCT, downstream forward: _UP4_TAAAAAAAGAGAGGATAGGC
References
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Time of last update: 2024-12-30 01:08:18
Author of last update: Melvin.boenninger