yfhF
168
general stress protein, similar to nucleoside-diphosphate sugar epimerase
locus
BSU_08510
Molecular weight
33.79 kDa
pI
9.93
function
survival of ethonol stress and at low temperatures
product
unknown
essential
no
synonyms
yfhF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1090 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
924,633 → 925,544
Phenotypes of a mutant
poorly transformable [pubmed|28189581]
The protein
Protein family
[wiki|NAD(P)-dependent epimerase/dehydratase family] (according to UniProt)
Structure
[PDB|3OH8] (from Corynebacterium glutamicum, 32% identity)
[AF|O31574]
Expression and Regulation
Operons
genes
[gene|B2924DAA879FBE56EB8DF9A7C60222AA1EE5526C|yfhF]-[gene|EE8065E719D0359B5892C8DCBCEC0B246ABE7D5B|yfhE]-[gene|29A9F7EEC3EFD8CA913877C41C1F00BCE9FF384D|yfhD]
description
[Pubmed|27965289]
regulation
expressed early during sporulation in the forespore ([protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]) [Pubmed|15699190]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|15699190], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|15699190], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
additional information
An [wiki|ncRNA] is predicted for '[protein|29A9F7EEC3EFD8CA913877C41C1F00BCE9FF384D|yfhD]' [PubMed|20525796]
Biological materials
Mutant
MGNA-C315 (yfhF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2313 NBRP B. subtilis, Japan]
BKE08510 (Δ[gene|B2924DAA879FBE56EB8DF9A7C60222AA1EE5526C|yfhF]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAACATCTCTCCTCATC, downstream forward: _UP4_TAAAAACAGCAGGAAGCGTC
BKK08510 (Δ[gene|B2924DAA879FBE56EB8DF9A7C60222AA1EE5526C|yfhF]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAACATCTCTCCTCATC, downstream forward: _UP4_TAAAAACAGCAGGAAGCGTC
References
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Time of last update: 2024-12-30 09:21:35
Author of last update: Jstuelk