yfhF

yfhF
168

general stress protein, similar to nucleoside-diphosphate sugar epimerase

locus
BSU_08510
Molecular weight
33.79 kDa
pI
9.93
Protein length
Gene length
function
survival of ethonol stress and at low temperatures
product
unknown
essential
no
synonyms
yfhF

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1090 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
924,633 → 925,544
Phenotypes of a mutant
poorly transformable [pubmed|28189581]
The protein
Protein family
[wiki|NAD(P)-dependent epimerase/dehydratase family] (according to UniProt)
Structure
[PDB|3OH8] (from Corynebacterium glutamicum, 32% identity)
[AF|O31574]
Expression and Regulation
Operons
genes
[gene|B2924DAA879FBE56EB8DF9A7C60222AA1EE5526C|yfhF]-[gene|EE8065E719D0359B5892C8DCBCEC0B246ABE7D5B|yfhE]-[gene|29A9F7EEC3EFD8CA913877C41C1F00BCE9FF384D|yfhD]
description
[Pubmed|27965289]
regulation
expressed early during sporulation in the forespore ([protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]) [Pubmed|15699190]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|15699190], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|15699190], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
additional information
An [wiki|ncRNA] is predicted for '[protein|29A9F7EEC3EFD8CA913877C41C1F00BCE9FF384D|yfhD]' [PubMed|20525796]
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[gene|B2924DAA879FBE56EB8DF9A7C60222AA1EE5526C|yfhF]→[gene|29A9F7EEC3EFD8CA913877C41C1F00BCE9FF384D|yfhD]

2024-10-08 16:11:50

Jstuelk

85

8ef3c8e68b6318191ec46b3f393f708cc2aeb6bd

AFE65A3C2533AC7AA5CC8859BB08B1B6EAF6B98C

Biological materials
Mutant
MGNA-C315 (yfhF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2313 NBRP B. subtilis, Japan]
BKE08510 (Δ[gene|B2924DAA879FBE56EB8DF9A7C60222AA1EE5526C|yfhF]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08510 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAACATCTCTCCTCATC,  downstream forward: _UP4_TAAAAACAGCAGGAAGCGTC
BKK08510 (Δ[gene|B2924DAA879FBE56EB8DF9A7C60222AA1EE5526C|yfhF]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08510 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAACATCTCTCCTCATC,  downstream forward: _UP4_TAAAAACAGCAGGAAGCGTC
References
15805528,28189581

B2924DAA879FBE56EB8DF9A7C60222AA1EE5526C

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Time of last update: 2024-10-10 15:43:23

Author of last update: Jstuelk