yjcD
168
similar to ATP-dependent DNA helicase
locus
BSU_11820
Molecular weight
86.79 kDa
pI
8.02
function
unknown
product
unknown
essential
no
synonyms
yjcD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0210 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,253,713 → 1,255,866
The protein
Catalyzed reaction/ biological activity
ATP + H2O --> ADP + H+ + phosphate (according to UniProt)
Protein family
[wiki|helicase family] (according to UniProt)
[wiki|Domains]
[wiki|UvrD-like helicase ATP-binding domain](aa 134-413) (according to UniProt)
[wiki|UvrD-like helicase C-terminal domain] (aa 414-676) (according to UniProt)
Structure
[PDB|2PJR] ([protein|C73E52D214E24F21696973B19B0A44CE785D6FBA|pcrA] product complex, complex with sulphate ion, ''Geobacillus stearothermophilus'', 36% identity, 55% similarity)
[PDB|1PJR] ([protein|C73E52D214E24F21696973B19B0A44CE785D6FBA|pcrA] substrate complex, complex with DNA, ''Geobacillus stearothermophilus'', 36% identity, 55% similarity)
[AF|O31626]
Paralogous protein(s)
[protein|C73E52D214E24F21696973B19B0A44CE785D6FBA|pcrA]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|B0789A727D9E3578FF1CB6162F365F45FADB0B3E|yjcD]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-A159 (yjcD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/159 NBRP B. subtilis, Japan]
BKE11820 (Δ[gene|B0789A727D9E3578FF1CB6162F365F45FADB0B3E|yjcD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE11820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAACGGGCTTTCCGCAAT, downstream forward: _UP4_TAACAGCCCGGCAGATTACT
BKK11820 (Δ[gene|B0789A727D9E3578FF1CB6162F365F45FADB0B3E|yjcD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK11820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAACGGGCTTTCCGCAAT, downstream forward: _UP4_TAACAGCCCGGCAGATTACT
References
Page visits: 2019
Time of last update: 2025-04-11 11:51:28
Author of last update: Melvin.boenninger