natA

natA
168

Na+ [wiki|ABC transporter ](export) (ATP-binding protein)

locus
BSU_02750
Molecular weight
27.73 kDa
pI
8.8
Protein length
Gene length
function
sodium export
product
Na+ [wiki|ABC transporter ](export) (ATP-binding protein)
essential
no
synonyms
natA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4555 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
296,429 → 297,169
The protein
Catalyzed reaction/ biological activity
ATP + H2O + Na+ --> ADP + H+ + Na+ + phosphate (according to UniProt)
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transporter domain] (aa 2-237) (according to UniProt)
Structure
[PDB|1VPL] (from Thermotoga maritima, 38% identity)
[AF|P46903]
[wiki|Localization]
membrane associated (via [protein|A8ADA02BBB549866DE330040CF6D06ECC3B00099|natB]) [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|B019FD0CB6F76C03DA5E76ABD1B324BA5E1A6936|natA]-[gene|A8ADA02BBB549866DE330040CF6D06ECC3B00099|natB]
description
[Pubmed|17322186]
regulatory mechanism
[protein|D3F6337B94A633730E514B05CA852BE9AA3741B3|natR]: activation, [Pubmed|17322186], in [regulon|protein:D3F6337B94A633730E514B05CA852BE9AA3741B3|natR regulon]
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[gene|B019FD0CB6F76C03DA5E76ABD1B324BA5E1A6936|natA]→[gene|A8ADA02BBB549866DE330040CF6D06ECC3B00099|natB]

2024-09-14 18:17:37

ghost

93

365bfdb79b01dbb624afc5261083cda7660bdab3

BD242E7EBA4710744BAD394FCF2B70F2317320EA

Biological materials
Mutant
BKE02750 (Δ[gene|B019FD0CB6F76C03DA5E76ABD1B324BA5E1A6936|natA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02750 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCACAATCTCCCTTAT,  downstream forward: _UP4_AAGCTTGTCAGGGGGATTTC
BKK02750 (Δ[gene|B019FD0CB6F76C03DA5E76ABD1B324BA5E1A6936|natA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02750 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTCACAATCTCCCTTAT,  downstream forward: _UP4_AAGCTTGTCAGGGGGATTTC
References
36815589,9106203,10092453,17322186

B019FD0CB6F76C03DA5E76ABD1B324BA5E1A6936

Page visits: 2660

Time of last update: 2024-10-07 10:37:30

Author of last update: Jstuelk