natA
168
Na+ [wiki|ABC transporter ](export) ([metabolite|ATP]-binding protein)
locus
BSU_02750
Molecular weight
27.73 kDa
pI
8.8
function
sodium export
product
Na+ [wiki|ABC transporter ](export) ([metabolite|ATP]-binding protein)
essential
no
synonyms
natA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4555 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
296,429 → 297,169
The protein
Catalyzed reaction/ biological activity
ATP + H2O + Na+ --> ADP + H+ + Na+ + phosphate (according to UniProt)
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transporter domain] (aa 2-237) (according to UniProt)
Structure
[PDB|1VPL] (from Thermotoga maritima, 38% identity)
[AF|P46903]
[wiki|Localization]
membrane associated (via [protein|A8ADA02BBB549866DE330040CF6D06ECC3B00099|natB]) [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|B019FD0CB6F76C03DA5E76ABD1B324BA5E1A6936|natA]-[gene|A8ADA02BBB549866DE330040CF6D06ECC3B00099|natB]
description
[Pubmed|17322186]
regulatory mechanism
[protein|D3F6337B94A633730E514B05CA852BE9AA3741B3|natR]: activation, [Pubmed|17322186], in [regulon|protein:D3F6337B94A633730E514B05CA852BE9AA3741B3|natR regulon]
Biological materials
Mutant
BKE02750 (Δ[gene|B019FD0CB6F76C03DA5E76ABD1B324BA5E1A6936|natA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02750 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCACAATCTCCCTTAT, downstream forward: _UP4_AAGCTTGTCAGGGGGATTTC
BKK02750 (Δ[gene|B019FD0CB6F76C03DA5E76ABD1B324BA5E1A6936|natA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02750 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCACAATCTCCCTTAT, downstream forward: _UP4_AAGCTTGTCAGGGGGATTTC
References
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Time of last update: 2024-12-21 12:29:24
Author of last update: Jstuelk