bmr
168
general stress protein, multidrug-efflux transporter
locus
BSU_24010
Molecular weight
42.10 kDa
pI
9.7
function
multidrug resistance
product
multidrug-efflux transporter
essential
no
synonyms
bmr, bmr1
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,494,656 2,495,825
The protein
Protein family
[wiki|major facilitator superfamily] (according to UniProt)
[wiki|TCR/Tet family] (according to UniProt)
Structure
[AF|P33449]
Paralogous protein(s)
[protein|B7C4BE1A252C6376B28C4FCC6EA9DCF3BC096405|blt]
Expression and Regulation
Operons
genes
[gene|ADBC0F194B601F736492E54011E0A68351B5BD39|bmr]-[gene|9F2C1C9A9DB7AA4CBE72D7C94932B69C8EF0565C|bmrR]
description
[Pubmed|7961792]
regulation
''[protein|search|bmrU]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]
regulatory mechanism
[protein|9F2C1C9A9DB7AA4CBE72D7C94932B69C8EF0565C|bmrR]: activation, [Pubmed|7961792], in [regulon|protein:9F2C1C9A9DB7AA4CBE72D7C94932B69C8EF0565C|bmrR regulon]
[protein|A7326377132C670B60695EFE0A652B1E4F623698|mta]: activation, [Pubmed|10200972], in [regulon|protein:A7326377132C670B60695EFE0A652B1E4F623698|mta regulon]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|10200972], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|88AECCE90DC0D6C92C61AB8860A31A830A8DAC42|bmrU]-[gene|ADBC0F194B601F736492E54011E0A68351B5BD39|bmr]-[gene|9F2C1C9A9DB7AA4CBE72D7C94932B69C8EF0565C|bmrR]
description
[Pubmed|10220166]
regulation
''[protein|search|bmrU]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
BKE24010 ([gene|ADBC0F194B601F736492E54011E0A68351B5BD39|bmr]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGACTTCCCCTTTTTC, downstream forward: _UP4_TGATAAGAAGCGCATTCTTT
BKK24010 ([gene|ADBC0F194B601F736492E54011E0A68351B5BD39|bmr]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGACTTCCCCTTTTTC, downstream forward: _UP4_TGATAAGAAGCGCATTCTTT
References
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Time of last update: 2024-12-30 23:39:25
Author of last update: Melvin.boenninger