ywcA
168
similar to Na+-dependent acetate symporter
locus
BSU_38240
Molecular weight
54.79 kDa
pI
7.2
function
unknown
product
unknown
essential
no
ec
null
synonyms
ywcA, ipa-31r
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4147 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,924,225 3,925,766
Phenotypes of a mutant
''[gene|4583EA9A4DF9F9EC054437CFB1C3849EA7BD49FA|ywcB]-[gene|ADB447B0F8EA4F341FA48344AA958E6B98B9EFE4|ywcA]'' mutant has slightly reduced acetic acid transport [Pubmed|26060272]
''[gene|4583EA9A4DF9F9EC054437CFB1C3849EA7BD49FA|ywcB]-[gene|ADB447B0F8EA4F341FA48344AA958E6B98B9EFE4|ywcA]'' mutant shows earlier pellicle biofilm formation [Pubmed|26060272]
The protein
Catalyzed reaction/ biological activity
the protein is involved in acetate transport [Pubmed|26060272]
the protein is not involved in proline transport [Pubmed|24142252]
Protein family
[wiki|sodium:solute symporter (SSF) (TC 2.A.21) family] (according to UniProt)
Structure
[AF|P39599]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|4583EA9A4DF9F9EC054437CFB1C3849EA7BD49FA|ywcB]-[gene|ADB447B0F8EA4F341FA48344AA958E6B98B9EFE4|ywcA]
regulation
expressed during sporulation ([protein|search|SigE]) [Pubmed|15699190]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
MGNA-B229 (ywcA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1228 NBRP B. subtilis, Japan]
available in [wiki|Erhard Bremer]'s lab [Pubmed|24142252]
BKE38240 ([gene|ADB447B0F8EA4F341FA48344AA958E6B98B9EFE4|ywcA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAATAATAAAAAAGCAGTCA, downstream forward: _UP4_TAAAAAAAGCTCTCTTTATC
BKK38240 ([gene|ADB447B0F8EA4F341FA48344AA958E6B98B9EFE4|ywcA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAATAATAAAAAAGCAGTCA, downstream forward: _UP4_TAAAAAAAGCTCTCTTTATC
References
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Time of last update: 2024-12-19 06:21:26
Author of last update: Melvin.boenninger