yerH
168
lipoprotein involved in cell division
locus
BSU_06630
Molecular weight
44.36 kDa
pI
4.88
function
unknown
product
unknown
essential
no
synonyms
yerH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4851 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
723,635 724,825
Phenotypes of a mutant
inactivation suppresses the essentiality of [gene|6ED386D49F973C1F6B1076974F54275DD583C9D3|mbl] [pubmed|39185233]
an [gene|B317D7E51824DD70EF84E4D5D7290D601BF4FAB6|ezrA] [gene|ADAE6B5C301959D90592A6F26DFE1690BF6F5552|yerH] double mutant has a severe growth defect [pubmed|39185233]
The protein
Structure
[PDB|4HN3] (from Listeria monocytogenes, 45% identity)
[AF|O34629]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|0BA7EC658F5C2397A90B68AC234D04966966561C|pcrB]-[gene|C73E52D214E24F21696973B19B0A44CE785D6FBA|pcrA]-[gene|03EFF93C1B0CE075AE068ECC4EDE9BE5D03C857E|ligA]-[gene|ADAE6B5C301959D90592A6F26DFE1690BF6F5552|yerH]
description
[Pubmed|9701819]
regulation
induced by DNA damage ([protein|search|LexA]) [Pubmed|16267290]
regulatory mechanism
[protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA]: repression, [Pubmed|16267290], in [regulon|protein:D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA regulon]
Biological materials
Mutant
MGNA-B445 (yerH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1444 NBRP B. subtilis, Japan]
BKE06630 ([gene|ADAE6B5C301959D90592A6F26DFE1690BF6F5552|yerH]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTTTTTCAATAGAAAACACT, downstream forward: _UP4_TGATAGAAAACCCTTGTGCC
BKK06630 ([gene|ADAE6B5C301959D90592A6F26DFE1690BF6F5552|yerH]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTTTTTCAATAGAAAACACT, downstream forward: _UP4_TGATAGAAAACCCTTGTGCC
References
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Time of last update: 2024-10-07 22:26:01
Author of last update: Jstuelk