glvR

glvR
168

transcriptional activator of the [gene|C650160C9E5B5F8587CA9E80A57BCCE97D701037|malA]-[gene|AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR]-[gene|E6C7733A12AF9A5322EED444E4A4FF1605A8B20F|malP] operon

locus
BSU_08190
Molecular weight
29.15 kDa
pI
5.45
Protein length
Gene length
function
regulation of maltose utilization
product
transcriptional activator
essential
no
ec
null
synonyms
glvR, yfiA, malR

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1737 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
891,436  892,200
The protein
[wiki|Domains]
HTH rpiR-type domain (aa 1-77) (according to UniProt)
[wiki|SIS domain] (aa 106-248) (according to UniProt)
Structure
[AF|P54717]
Expression and Regulation
Operons
genes
[gene|C650160C9E5B5F8587CA9E80A57BCCE97D701037|malA]-[gene|AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR]-[gene|E6C7733A12AF9A5322EED444E4A4FF1605A8B20F|malP]
description
[Pubmed|11489864]
regulation
induction by maltose ([protein|search|GlvR]) [Pubmed|11489864]
regulatory mechanism
[protein|AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR]: activation, [Pubmed|11489864], in [regulon|protein:AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|11489864], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|11489864], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|C650160C9E5B5F8587CA9E80A57BCCE97D701037|malA]→[gene|E6C7733A12AF9A5322EED444E4A4FF1605A8B20F|malP]

2024-12-09 01:00:43

ghost

84

6a26149dfa8d59e889feb231a4a368771031054a

FD8255D46CE7F0F8F2F29E2D8219342876F518B7

Biological materials
Mutant
MGNA-C290 (yfiA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2288 NBRP B. subtilis, Japan]
BKE08190 ([gene|AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08190 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATCAGATCCCCCCATTT,  downstream forward: _UP4_AATGACAATGAGTAGCAGGGG
BKK08190 ([gene|AD72489DA260F07B97A213F1F0FBA7CED9471817|glvR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08190 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATCAGATCCCCCCATTT,  downstream forward: _UP4_AATGACAATGAGTAGCAGGGG
References
11489864

AD72489DA260F07B97A213F1F0FBA7CED9471817

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Time of last update: 2024-12-25 19:43:27

Author of last update: Jstuelk