yktC

yktC
168

inositol monophosphatase and 5'-nucleotidase with preference for GMP and IMP

locus
BSU_14670
Molecular weight
29.61 kDa
pI
5.09
Protein length
Gene length
function
unknown
product
nucleotidase
essential
no
ec
3.1.3.25
synonyms
yktC, suhB

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0483 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,537,441  1,538,238
Phenotypes of a mutant
sensitive to diamide stress [Pubmed|27784292]
The protein
Catalyzed reaction/ biological activity
myo-inositol phosphate + H2O --> myo-inositol + phosphate (according to UniProt)
Protein family
inositol monophosphatase superfamily (single member, according to UniProt)
Structure
[PDB|5I3S] (from Staphylococcus aureus, 51% identity)
[AF|Q45499]
Expression and Regulation
Operons
genes
[gene|AD151804FC145854DB6BAA12CD52758FB1C3882F|yktC]-[gene|A313B197D6D885EEE7F739E1F137794A8E3AD8F9|ykzC]
description
[pubmed|22383849]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|26577401], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
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[gene|AD151804FC145854DB6BAA12CD52758FB1C3882F|yktC]->[gene|A313B197D6D885EEE7F739E1F137794A8E3AD8F9|ykzC]

2024-08-27 03:03:28

Bzhu

41

133db3115c3287426f3d0993352a6cd7e2ce853b

51CBFA564E58E1077A5A313A4FB9C32F92524956

Biological materials
Mutant
MGNA-A908 (yktC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/908 NBRP B. subtilis, Japan]
BKE14670 ([gene|AD151804FC145854DB6BAA12CD52758FB1C3882F|yktC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14670 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCGTTCGTACCTCTCTT,  downstream forward: _UP4_TAGGCCATTTGAGCAGGATG
BKK14670 ([gene|AD151804FC145854DB6BAA12CD52758FB1C3882F|yktC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14670 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCGTTCGTACCTCTCTT,  downstream forward: _UP4_TAGGCCATTTGAGCAGGATG
References
19935659,26577401,27784292

AD151804FC145854DB6BAA12CD52758FB1C3882F

Page visits: 2198

Time of last update: 2024-10-10 20:24:57

Author of last update: Melvin.boenninger