etfA
168
electron transfer flavoprotein (alpha subunit)
locus
BSU_28520
Molecular weight
34.39 kDa
pI
4.65
function
fatty acid degradation, calcium carbonate biomineralization
product
electron transfer flavoprotein (alpha subunit)
essential
no
synonyms
etfA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2025 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,915,365 2,916,342
The protein
Protein family
ETF alpha-subunit/fixB family (single member, according to UniProt)
[wiki|Cofactors]
FAD (according to UniProt)
Structure
[PDB|1EFV] (the human protein, 39% identity) [pubmed|8962055]
[AF|P94551]
Expression and Regulation
Operons
genes
[gene|7AC5217CA35F8E134ABB35D74F1BA5E684D2E058|lcfA]-[gene|8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR]-[gene|3111ECB66CD3CFF0494AA3DF4D646102CF3B0FA8|fadB]-[gene|251600E5FD52DC0352A123F1224C037577F5A09C|etfB]-[gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]
description
[Pubmed|17189250]
regulation
induced by long chain acyl-CoA (C14 ... C20) ([protein|8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR]) [Pubmed|17189250]
regulatory mechanism
[protein|8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR]: repression, [Pubmed|17189250], in [regulon|protein:8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|21398533], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21398533], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR]-[gene|3111ECB66CD3CFF0494AA3DF4D646102CF3B0FA8|fadB]-[gene|251600E5FD52DC0352A123F1224C037577F5A09C|etfB]-[gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]
description
[Pubmed|17189250]
regulation
induced by long-chain fatty acids ([protein|search|FadR]) [Pubmed|17189250]
Biological materials
Mutant
1A856 ( ''etfA''::''cat''), [Pubmed|17085570], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A856&Search=1A856 BGSC]
BKE28520 ([gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE28520 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTAACATCCCCCTGTT, downstream forward: _UP4_TAAAGGAAATCCCGGACTTT
BKK28520 ([gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK28520 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTAACATCCCCCTGTT, downstream forward: _UP4_TAAAGGAAATCCCGGACTTT
References
Reviews
Original Publications
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Time of last update: 2024-12-26 13:36:02
Author of last update: Jstuelk