psdB

psdB
168

[wiki|ABC transporter] (permease) for the export of lipid II-binding lantibiotics, such as nisin and gallidermin

locus
BSU_34690
Molecular weight
73.22 kDa
pI
9.8
Protein length
Gene length
function
export of toxic peptides
product
[wiki|ABC transporter] (permease)
essential
no
synonyms
psdB, yvcS

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0577 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,563,581  3,565,521
The protein
Protein family
[wiki|ABC-4 integral membrane protein family] (according to UniProt)
Structure
[AF|O06981]
Paralogous protein(s)
[protein|4423383A3F6DAFDFA210F4BEEF7D8CBEC674DCEA|yxdM]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|985E7F25C809AA5DF372101E64960DF704EED53F|psdR]-[gene|A9525886E911164BDFF0A55DA9F5FDD1C1B7A3B6|psdS]-[gene|464DD1855E6B3195EE242637612A16C73FF32FC0|psdA]-[gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]
description
[Pubmed|21078927]
regulation
''[protein|search|psdA]'': induced by nisin, gallidermin ([protein|search|PsdR]) [Pubmed|21078927]
regulatory mechanism
[protein|985E7F25C809AA5DF372101E64960DF704EED53F|psdR]: activation, [Pubmed|21078927], in [regulon|protein:985E7F25C809AA5DF372101E64960DF704EED53F|psdR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21078927], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Open in new tab

[gene|985E7F25C809AA5DF372101E64960DF704EED53F|psdR]→[gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]

2024-10-10 15:34:06

ghost

55

d7c5e7b0711e6228a3cdf2a71273ad8f725b7c09

5FD7CD564F41C61165A1333E78C1CCE35B7CF017

genes
[gene|464DD1855E6B3195EE242637612A16C73FF32FC0|psdA]-[gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]
description
[Pubmed|18394148]
regulation
''[protein|search|psdA]'': induced by nisin, gallidermin ([protein|search|PsdR]) [Pubmed|21078927]
Open in new tab

[gene|464DD1855E6B3195EE242637612A16C73FF32FC0|psdA]→[gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]

2024-10-08 13:19:38

ghost

69

528cfddc9a2a0d8255143057e419a826bbda2cca

A575053EE656C7505582CC0B07D1C34F3FE06BD1

Biological materials
Mutant
MGNA-B634 (yvcS::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1633 NBRP B. subtilis, Japan]
BKE34690 ([gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE34690 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CCGTTGCAGATTCCCAAGAA,  downstream forward: _UP4_TAATATGAAATCCGGTCTGT
BKK34690 ([gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK34690 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CCGTTGCAGATTCCCAAGAA,  downstream forward: _UP4_TAATATGAAATCCGGTCTGT
References
Reviews
38869304
Original Publications
18394148,10092453,21283517

AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC

Page visits: 2780

Time of last update: 2024-10-10 17:34:55

Author of last update: Jstuelk