psdB
168
[wiki|ABC transporter] (permease) for the export of lipid II-binding lantibiotics, such as nisin and gallidermin
locus
BSU_34690
Molecular weight
73.22 kDa
pI
9.8
function
export of toxic peptides
product
[wiki|ABC transporter] (permease)
essential
no
synonyms
psdB, yvcS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0577 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,563,581 3,565,521
The protein
Protein family
[wiki|ABC-4 integral membrane protein family] (according to UniProt)
Structure
[AF|O06981]
Paralogous protein(s)
[protein|4423383A3F6DAFDFA210F4BEEF7D8CBEC674DCEA|yxdM]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|985E7F25C809AA5DF372101E64960DF704EED53F|psdR]-[gene|A9525886E911164BDFF0A55DA9F5FDD1C1B7A3B6|psdS]-[gene|464DD1855E6B3195EE242637612A16C73FF32FC0|psdA]-[gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]
description
[Pubmed|21078927]
regulation
''[protein|search|psdA]'': induced by nisin, gallidermin ([protein|search|PsdR]) [Pubmed|21078927]
regulatory mechanism
[protein|985E7F25C809AA5DF372101E64960DF704EED53F|psdR]: activation, [Pubmed|21078927], in [regulon|protein:985E7F25C809AA5DF372101E64960DF704EED53F|psdR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21078927], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|464DD1855E6B3195EE242637612A16C73FF32FC0|psdA]-[gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]
description
[Pubmed|18394148]
regulation
''[protein|search|psdA]'': induced by nisin, gallidermin ([protein|search|PsdR]) [Pubmed|21078927]
Biological materials
Mutant
MGNA-B634 (yvcS::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1633 NBRP B. subtilis, Japan]
BKE34690 ([gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE34690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCGTTGCAGATTCCCAAGAA, downstream forward: _UP4_TAATATGAAATCCGGTCTGT
BKK34690 ([gene|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|psdB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK34690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCGTTGCAGATTCCCAAGAA, downstream forward: _UP4_TAATATGAAATCCGGTCTGT
References
Reviews
Original Publications
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Time of last update: 2024-12-30 02:30:39
Author of last update: Jstuelk