pmi
168
mannose-6-phosphate isomerase
locus
BSU_35790
Molecular weight
35.27 kDa
pI
4.98
function
mannose utilization
product
mannose-6-phosphate isomerase
essential
no
ec
5.3.1.8
synonyms
pmi, yvyI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1482 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,687,597 3,688,547
The protein
Catalyzed reaction/ biological activity
D-mannose 6-phosphate --> D-fructose 6-phosphate (according to UniProt)
Protein family
mannose-6-phosphate isomerase type 1 family (with [protein|E26C70893C5D677C816C814558CC42F90B920087|manA] and [protein|35225776F6044513D3E77DBBD6A7A8FE976F506A|gmuF], according to UniProt)
Structure
[PDB|1QWR]
[AF|P39841]
Paralogous protein(s)
[protein|E26C70893C5D677C816C814558CC42F90B920087|manA], [protein|35225776F6044513D3E77DBBD6A7A8FE976F506A|gmuF]
Expression and Regulation
Operons
genes
[gene|AC79E2A80664B4D165A0AE46CEA124C57EB9770D|pmi]
description
[Pubmed|7934877]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|7934877], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
BKE35790 ([gene|AC79E2A80664B4D165A0AE46CEA124C57EB9770D|pmi]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE35790 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATCCGTACCCCTCCCC, downstream forward: _UP4_TAAACTTAATCTCACTTCGA
BKK35790 ([gene|AC79E2A80664B4D165A0AE46CEA124C57EB9770D|pmi]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK35790 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATCCGTACCCCTCCCC, downstream forward: _UP4_TAAACTTAATCTCACTTCGA
References
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Time of last update: 2024-11-09 03:18:47
Author of last update: Melvin.boenninger