rsbV
168
antagonist of [protein|5AF5F199C5D92E13DE1C56E28948A557E3954CBF|rsbW], anti-anti-[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]
locus
BSU_04710
Molecular weight
11.80 kDa
pI
4.7
function
control of [protein|search|SigB ]activity
product
anti-anti-[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]
essential
no
synonyms
rsbV
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1366 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
522,088 522,417
The protein
Protein family
anti-sigma-factor antagonist family (with [protein|3936E91C062074BFE4284B54A8CC33F35F94F5EE|spoIIAA], according to UniProt)
[wiki|Domains]
[wiki|STAS domain] (aa 3-109) (according to UniProt)
Structure
[PDB|1VC1] (homolog from Thermotoga maritima)
[AF|P17903]
Modification
phosphorylation on Ser-52 AND Ser-56 by [protein|5AF5F199C5D92E13DE1C56E28948A557E3954CBF|rsbW] [Pubmed|17218307], [Pubmed|17726680]
Expression and Regulation
Operons
genes
[gene|621357D1FB6AC1B0499732EFE226F982B26CE34E|rsbR]-[gene|841CE7FCA4E84445830CA18F9856F6F30014E3BB|rsbS]-[gene|ADC52A22950736A0435AEEEC43F7407878786A81|rsbT]-[gene|0B8381D2C724DAA724E4AFC67000F12AD112D13D|rsbU]-[gene|AC64DA463250A090A62E50901EFE653C8F963872|rsbV]-[gene|5AF5F199C5D92E13DE1C56E28948A557E3954CBF|rsbW]-[gene|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]-[gene|8536803BDFB58D43C52961931F609933E49E989D|rsbX]
description
[Pubmed|8002610]
regulation
''[protein|search|rsbV]:'' induced by stress ([protein|search|SigB]) [Pubmed|11544224]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|20454630], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8002610], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
genes
[gene|AC64DA463250A090A62E50901EFE653C8F963872|rsbV]-[gene|5AF5F199C5D92E13DE1C56E28948A557E3954CBF|rsbW]-[gene|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]-[gene|8536803BDFB58D43C52961931F609933E49E989D|rsbX]
description
[Pubmed|2170324]
regulation
''[protein|search|rsbV]:'' induced by stress ([protein|search|SigB]) [Pubmed|11544224]
Biological materials
Mutant
BKE04710 ([gene|AC64DA463250A090A62E50901EFE653C8F963872|rsbV]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCGTATCACCTCAAATT, downstream forward: _UP4_GCAAAGTCAGAAGGTGGAGT
BKK04710 ([gene|AC64DA463250A090A62E50901EFE653C8F963872|rsbV]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCGTATCACCTCAAATT, downstream forward: _UP4_GCAAAGTCAGAAGGTGGAGT
labs
[wiki|Bill Haldenwang], San Antonio, USA
[wiki|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]
References
Reviews
Original Publications
Page visits: 4825
Time of last update: 2024-12-19 19:12:31
Author of last update: Jstuelk