rlmH
168
pseudouridine methyltransferase, required for methylation of pseudouridine at position 1944 of 23S rRNA
locus
BSU_40230
Molecular weight
17.93 kDa
pI
9.31
function
maturation of 23S rRNA
product
pseudouridine methyltransferase
essential
no
ec
null
synonyms
yydA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1576 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
4,134,436 4,134,915
The protein
Catalyzed reaction/ biological activity
pseudouridine1944 in 23S rRNA + S-adenosyl-L-methionine --> H+ + N3-methylpseudouridine1944 in 23S rRNA + S-adenosyl-L-homocysteine [pubmed|39036956]
Protein family
RNA methyltransferase rlmH family (single member, according to UniProt)
Structure
[PDB|1TO0]
[AF|Q45601]
Expression and Regulation
Operons
genes
[gene|AC2A9DC3DA569231442582A95EDB2A98BA335184|rlmH]
description
null
regulatory mechanism
[protein|6740108089F13116F200C15F35C2E7561E990FEB|dnaA]: repression, [Pubmed|17932079], in [regulon|protein:6740108089F13116F200C15F35C2E7561E990FEB|dnaA regulon]
genes
[gene|660FD9F2AC911E4E70E242F14A2EA6A208F25E28|yyzF]-[gene|AC2A9DC3DA569231442582A95EDB2A98BA335184|rlmH]-[gene|F30AA652362B7459D479345AB373D19FA1EAFBBF|yydB]-[gene|235399FB29FA7443D41AA9543EEB18F195503091|yydC]-[gene|1470E1E1BAE5EA5BA9831E2BCEF9B61E79450510|yydD]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-B814 (yydA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1813 NBRP B. subtilis, Japan]
References
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Time of last update: 2024-12-22 08:35:59
Author of last update: Jstuelk