dnaI

dnaI
168

[wiki|primosome] component (helicase loader), part of the [wiki|replisome]

locus
BSU_28980
Molecular weight
35.96 kDa
pI
5.74
Protein length
311 aaSequenceBlast
Gene length
936 bpSequenceBlast
function
[category|SW.3.1.1|DNA replication]
product
[wiki|primosome] component (helicase loader)
essential
yes
synonyms
dnaI, ytxA, dnaY
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1484 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,963,185  2,964,120
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Structure
[PDB|2K7R] (N-terminal domain)
[PDB|4M4W] (the [protein|5CF09E089AA70A32F640CE0D33D1F05312AAE24D|dnaC]-[protein|AC1B507C6B1640E9BEA1F9F01628120F3680C976|dnaI]-[protein|F7B53E8AC92DAD15544C6208C2A5B41BABA73D6D|dnaG] complex) [Pubmed|24048025]
[AF|P06567]
[wiki|Localization]
cell membrane (according to Swiss-Prot),  Cytoplasm (Homogeneous) [Pubmed|16479537] forms foci, close to oriC [Pubmed|10844689]
Expression and Regulation
Operons
genes
[gene|2AEF6D56D884CA6A0BD50FABD27F405DC2B506C7|dnaB]-[gene|AC1B507C6B1640E9BEA1F9F01628120F3680C976|dnaI]-[gene|72A4458679EA1451FA3B63D44C3BE93ACA8B397F|ytxB]-[gene|3EE0D03469D893515CAA4961BF923BE3A6769535|ytxC]-[gene|3E1131CFA3EDEB3865638F09BE2F6B6ED2570BE2|thrS]
description
[Pubmed|22383849]
Open in new tab

[gene|2AEF6D56D884CA6A0BD50FABD27F405DC2B506C7|dnaB]→[gene|3E1131CFA3EDEB3865638F09BE2F6B6ED2570BE2|thrS]

2024-12-23 05:57:15

Jstuelk

124

86944789c9fccd66104bd44b9e445a3dc0b7ffc0

B3B673302E6466DA20A850B2B832501BE5C0DACF

References
Reviews
22797751,28075389,36877032
Original Publications
19255093,10844689,12718886,11842108,20122408,16479537,19744498,19255093,19968790,11679082,24048025,30285297

AC1B507C6B1640E9BEA1F9F01628120F3680C976

Page visits: 4749

Time of last update: 2024-12-30 08:34:08

Author of last update: Jstuelk