mrpB

mrpB
168

Na+/H+ antiporter subunit, multiple resistance and pH homeostasis

locus
BSU_31610
Molecular weight
15.15 kDa
pI
4.91
Protein length
Gene length
function
sodium export
product
Na+/H+ antiporter subunit
essential
yes
synonyms
mrpB, yufU

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2111 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,248,996  3,249,427
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Protein family
CPA3 antiporters (TC 2.A.63) subunit B family (single member, according to UniProt)
Structure
[PDB|6CFW] (from Pyrococcus furiosus, corresponds to aa 1 ... 104, 31% identity) [pubmed|29754813]
[AF|O05259]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|E968DECF869CAF7E247A518494AD70B554A7A25F|mrpA]-[gene|AAB15E7E3E3701AA3159370B85C151994244BA5B|mrpB]-[gene|D921139B18A665E9BB177C973FCF050A4BFFF97F|mrpC]-[gene|051D9BCC0CB05E39ED5825BB9BA77B8228EA055D|mrpD]-[gene|BF233467FAF95EEEE12A0D36C543DB357D8879EA|mrpE]-[gene|5CA2EA2D60FE4696903C16698C8329A20CBEBF72|mrpF]-[gene|B28796716C7E6C924F55176453DDBF9ADD0EF755|mrpG]
description
[Pubmed|9274030,10198001]
Open in new tab

[gene|E968DECF869CAF7E247A518494AD70B554A7A25F|mrpA]→[gene|B28796716C7E6C924F55176453DDBF9ADD0EF755|mrpG]

2024-10-08 04:19:16

ghost

79

0833d14430981483bcfaa13a7a8e288e077b523f

4FC54E916920821D8932F58F7DE85186D61907A1

Biological materials
Mutant
MGNA-B558 (yufU::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1557 NBRP B. subtilis, Japan]
SM-GN9 (mrpB-spc), available in [wiki|Anne Galinier]'s and [wiki|Boris Görke]'s labs
References
Reviews
29218041
Original Publications
11004162,9274030,10198001,19389778,17693497,18408029,29754813

AAB15E7E3E3701AA3159370B85C151994244BA5B

Page visits: 2300

Time of last update: 2024-10-12 07:05:06

Author of last update: Melvin.boenninger