ykuI
168
c-di-GMP binding protein
locus
BSU_14090
Molecular weight
47.80 kDa
pI
4.46
function
unknown
product
c-di-GMP binding protein
essential
no
synonyms
ykuI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2200 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,482,248 1,483,471
Phenotypes of a mutant
inactivation of ''[gene|A9C45C522EAF534C41CB75AA364A379E1D11055F|ykuI]'' confers resistance to high concentrations of Zn(II) [Pubmed|27935957]
The protein
[wiki|Domains]
EAL domain (aa 1-250) (according to UniPort)
PAS-like domain (aa 300-400) [Pubmed|19244251]
Structure
[PDB|2BAS]
in complex with c-di-GMP [PDB|2W27] [Pubmed|19244251]
[AF|O35014]
Expression and Regulation
Operons
genes
[gene|69E475F00D9CCFDDF086F0B8A5CBA81B31DD06FE|ykuH]-[gene|A9C45C522EAF534C41CB75AA364A379E1D11055F|ykuI]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-A770 (ykuI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/770 NBRP B. subtilis, Japan]
GP1324 (tet), available in [wiki|Jörg Stülke]'s lab
BKE14090 ([gene|A9C45C522EAF534C41CB75AA364A379E1D11055F|ykuI]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTATCACCTGCTTCTC, downstream forward: _UP4_TAACGGCTGAAAGGCCGTTT
BKK14090 ([gene|A9C45C522EAF534C41CB75AA364A379E1D11055F|ykuI]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTATCACCTGCTTCTC, downstream forward: _UP4_TAACGGCTGAAAGGCCGTTT
References
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Time of last update: 2024-12-05 20:41:37
Author of last update: Melvin.boenninger