adeR
168
transcription activator ([wiki|PucR family]) for [gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald] gene expression
locus
BSU_31920
Molecular weight
50.14 kDa
pI
8.15
function
control of [gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald] expression
product
transcription activator ([wiki|PucR family])
essential
no
synonyms
adeR, yukF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2508 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,276,955 3,278,223
Phenotypes of a mutant
[wiki|sporulation] defect due to lack of ''[gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald]'' expression [Pubmed|22797752]
The protein
Catalyzed reaction/ biological activity
transcription activation of ''[gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald]'' gene expression in the presence of alanine [Pubmed|22797752]
Protein family
[wiki|PucR family]
[wiki|CdaR family] (according to UniProt)
Structure
[AF|P71073]
Modification
phosphorylated on Ser-395 [Pubmed|20509597]
Effectors of protein activity
L-alanine [Pubmed|22797752]
Expression and Regulation
Operons
genes
[gene|A987E1510578E8DE822C2019488D457CB7CFBE73|adeR]
description
[Pubmed|8226620]
regulation
constitutively expressed [Pubmed|22797752]
Biological materials
Mutant
MGNA-A631 (yukF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/631 NBRP B. subtilis, Japan]
BKE31920 ([gene|A987E1510578E8DE822C2019488D457CB7CFBE73|adeR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCATCCCCTTCCTTTT, downstream forward: _UP4_TGAAATTTCACAAATCCATG
BKK31920 ([gene|A987E1510578E8DE822C2019488D457CB7CFBE73|adeR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCATCCCCTTCCTTTT, downstream forward: _UP4_TGAAATTTCACAAATCCATG
References
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Time of last update: 2024-10-07 15:59:32
Author of last update: Melvin.boenninger