adeR

adeR
168

transcription activator ([wiki|PucR family]) for [gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald] gene expression

locus
BSU_31920
Molecular weight
50.14 kDa
pI
8.15
Protein length
Gene length
function
control of [gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald] expression
product
transcription activator ([wiki|PucR family])
essential
no
synonyms
adeR, yukF

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2508 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,276,955  3,278,223
Phenotypes of a mutant
[wiki|sporulation] defect due to lack of ''[gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald]'' expression [Pubmed|22797752]
The protein
Catalyzed reaction/ biological activity
transcription activation of ''[gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald]'' gene expression in the presence of alanine [Pubmed|22797752]
Protein family
[wiki|PucR family]
[wiki|CdaR family] (according to UniProt)
Structure
[AF|P71073]
Modification
phosphorylated on Ser-395 [Pubmed|20509597]
Effectors of protein activity
L-alanine [Pubmed|22797752]
Expression and Regulation
Operons
genes
[gene|A987E1510578E8DE822C2019488D457CB7CFBE73|adeR]
description
[Pubmed|8226620]
regulation
constitutively expressed [Pubmed|22797752]
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[gene|A987E1510578E8DE822C2019488D457CB7CFBE73|adeR]

2024-12-21 12:07:55

ghost

43

6b488aa271f8b7077cfefc10d23c554bd2a2da4b

51EF81BDA90FF0B15A239A6310282DC6E5998BEE

Biological materials
Mutant
MGNA-A631 (yukF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/631 NBRP B. subtilis, Japan]
BKE31920 ([gene|A987E1510578E8DE822C2019488D457CB7CFBE73|adeR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTCATCCCCTTCCTTTT,  downstream forward: _UP4_TGAAATTTCACAAATCCATG
BKK31920 ([gene|A987E1510578E8DE822C2019488D457CB7CFBE73|adeR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTCATCCCCTTCCTTTT,  downstream forward: _UP4_TGAAATTTCACAAATCCATG
References
8226620,20509597,22797752

A987E1510578E8DE822C2019488D457CB7CFBE73

Page visits: 2694

Time of last update: 2024-12-27 17:57:05

Author of last update: Melvin.boenninger