spo0E

spo0E
168

Spo0A-P phosphatase, control of the phosphorelay

locus
BSU_13640
Molecular weight
9.65 kDa
pI
6.48
Protein length
85 aaSequenceBlast
Gene length
258 bpSequenceBlast
function
initiation of sporulation
product
Spo0A-P phosphatase
essential
no
synonyms
spo0E
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5804 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,430,684  1,430,941
The protein
Protein family
spo0E family (with [protein|search|ynzd ]and [protein|022933D89666CDD2ACE39BCBB78D349BAF8E899B|yisI], according to UniProt)
Structure
[AF|P05043]
Paralogous protein(s)
[protein|A2250786C40A23A5EBD830B3853DE5187B3D24EC|ynzD]
Expression and Regulation
Operons
genes
[gene|A574974B6F4FF46DC69E03AE021651C67089866F|spo0E]
description
[Pubmed|2838724]
regulation
induced under stress conditions ([protein|search|SigB]) [Pubmed|22210769]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|2504584], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
[protein|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|rok]: repression, of the [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]-dependent promoter [Pubmed|22524514], in [regulon|protein:1508770D5BCA5739D13E3ABD11CC5C103C07FF25|rok regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|1901567], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|22210769], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
additional information
Spo0E is degraded by [protein|search|FtsH]
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[gene|A574974B6F4FF46DC69E03AE021651C67089866F|spo0E]

2024-12-21 12:44:50

ghost

61

e240f8f72c3814c0f6d6aaec24c7f1f6360a00c8

074269D810741184F6906C392682ECB7E00AFA39

Biological materials
Mutant
BKE13640 ([gene|A574974B6F4FF46DC69E03AE021651C67089866F|spo0E]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE13640 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCACTTCACCCCTCGCC,  downstream forward: _UP4_TAGCGGCCTATCAGATGCAT
BKK13640 ([gene|A574974B6F4FF46DC69E03AE021651C67089866F|spo0E]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK13640 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCACTTCACCCCTCGCC,  downstream forward: _UP4_TAGCGGCCTATCAGATGCAT
labs
[wiki|Tony Wilkinson], York University, U.K. [http://www.york.ac.uk/depts/chem/staff/ajw.html homepage]
References
Reviews
19995980,35638784
Original Publications
2838724,1901567,8127878,11112444,11679073,12067336,15916600,15057450,17001075,18045868,19050850,19332814,22524514,22210769,2504584,22142536

A574974B6F4FF46DC69E03AE021651C67089866F

Page visits: 4496

Time of last update: 2024-12-21 11:15:41

Author of last update: Jstuelk