yhcS
168
sortase
locus
BSU_09200
Molecular weight
21.83 kDa
pI
7.17
function
anchoring of proteins to the cell wall
product
sortase
essential
no
synonyms
yhcS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3764 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
994,998 995,594
The protein
Catalyzed reaction/ biological activity
C-terminal anchoring of proteins to the cell wall
Protein family
bacterial sortase family (with [protein|B17670494CC6F7C1138F4B4ECC0FEE8FC15609A2|ywpE], according to UniProt)
Structure
[PDB|2LN7] (B. anthracis SrtD, corresponds to aa 69 - 195 of YhcS, 44% identity) [pubmed|22974341]
[AF|P54603]
[wiki|Localization]
membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|DAFBC470DA0FA437B117716DE899A8D3EC454672|yhcR]-[gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-A661 (yhcS::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/661 NBRP B. subtilis, Japan]
BKE09200 ([gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGAATAGTGGAATAACTT, downstream forward: _UP4_TAAAAAGCCGAGGCAGTGCC
BKK09200 ([gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGAATAGTGGAATAACTT, downstream forward: _UP4_TAAAAAGCCGAGGCAGTGCC
References
Reviews
Original Publications
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Time of last update: 2024-12-21 23:32:24
Author of last update: Melvin.boenninger