mhqN
168
similar to NAD(P)H nitroreductase
locus
BSU_05480
Molecular weight
23.41 kDa
pI
5.56
function
unknown
product
unknown
essential
no
synonyms
mhqN, ydfN
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0778 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
596,478 597,098
The protein
Protein family
[wiki|nitroreductase family] (according to UniProt)
Structure
[PDB|3BEM]
[AF|P96692]
Expression and Regulation
Operons
genes
[gene|A0842DD5F1B13AC15C95F18751E7836DF31B262A|mhqN]-[gene|ACAFB2072E74CC059B492A31EF492028B96C569F|mhqO]-[gene|B4384C8C0874BAA7822E9B6DCAB57790018271D8|mhqP]
description
[Pubmed|17725564]
regulation
induced by catechol and 2-methylhydroquinone ([protein|search|MhqR]) [Pubmed|17725564]
regulatory mechanism
[protein|997B828A99D6D8460712C18ED0CE566B285C22DC|mhqR]: repression, [Pubmed|17725564], in [regulon|protein:997B828A99D6D8460712C18ED0CE566B285C22DC|mhqR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|17725564], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-C153 (ydfN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2151 NBRP B. subtilis, Japan]
BKE05480 ([gene|A0842DD5F1B13AC15C95F18751E7836DF31B262A|mhqN]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTACGCTACACTCCCTTT, downstream forward: _UP4_TATATGTAAAAGGAGCGGAT
BKK05480 ([gene|A0842DD5F1B13AC15C95F18751E7836DF31B262A|mhqN]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTACGCTACACTCCCTTT, downstream forward: _UP4_TATATGTAAAAGGAGCGGAT
lacZ fusion
BP1112: Promotor-lacZ fusion, available at [wiki|Jörg Stülke]'s and [wiki|Fabian Commichau]'s labs
References
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Time of last update: 2025-04-17 20:01:40
Author of last update: Melvin.boenninger