yfjR
168
similar to 3-hydroxyisobutyrate dehydrogenase
locus
BSU_07990
Molecular weight
27.72 kDa
pI
4.78
function
unknown
product
3-hydroxyisobutyrate dehydrogenase
essential
no
synonyms
yfjR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2084 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
870,388 871,248
The protein
Protein family
HIBADH-related family (with [protein|1010B1028A9A5F234C33474C7BC23C9BD2ABF3C4|ykwC], according to UniProt)
Structure
[PDB|4GBJ] (from ''Dyadobacter Fermentans'', 41% identity)
[AF|O34969]
Modification
phosphorylated on ser/ thr/ tyr [Pubmed|16493705]
Paralogous protein(s)
[protein|1010B1028A9A5F234C33474C7BC23C9BD2ABF3C4|ykwC], (32%)
Expression and Regulation
Operons
genes
[gene|9F8A63C585227D59C8A5CD4356E3F81EB5897131|yfjR]
description
[pubmed|22383849]
regulatory mechanism
[protein|706983E6942E883D3A9D45693E7B4015AEABE60B|yclJ]: activation, [Pubmed|20512483], in [regulon|protein:706983E6942E883D3A9D45693E7B4015AEABE60B|yclJ regulon]
Biological materials
Mutant
MGNA-C350 (yfjR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2348 NBRP B. subtilis, Japan]
BKE07990 ([gene|9F8A63C585227D59C8A5CD4356E3F81EB5897131|yfjR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE07990 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATCTAATCACTCCCTGAA, downstream forward: _UP4_TAAAGAAAAGCCTCTCCGTT
BKK07990 ([gene|9F8A63C585227D59C8A5CD4356E3F81EB5897131|yfjR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK07990 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATCTAATCACTCCCTGAA, downstream forward: _UP4_TAAAGAAAAGCCTCTCCGTT
References
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Time of last update: 2024-10-02 22:08:33
Author of last update: Melvin.boenninger