ctaE
168
cytochrome-c oxidase (caa3) (subunit III)
locus
BSU_14910
Molecular weight
23.12 kDa
pI
7.41
function
respiration
product
cytochrome-c oxidase (subunit III)
essential
no
ec
1.9.3.1
synonyms
ctaE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1845 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,563,437 1,564,060
The protein
Catalyzed reaction/ biological activity
4 [Fe(II)cytochrome c] + 4 H+ + O2 --> 4 [Fe(III)cytochrome c] + 2 H2O (according to UniProt)
Protein family
cytochrome c oxidase subunit 3 family (with [protein|CD4520EF427AEFDCF028AE063BC373FA6DCE379E|qoxC], according to UniProt)
Structure
[PDB|1FFT] (ubichinol oxidase from E. coli, 43% identity) [pubmed|11017202]
[AF|P24012]
[wiki|Localization]
cell membrane [Pubmed|23880299]
Expression and Regulation
Operons
genes
[gene|83F5D5FCCAFADB7231ACD9BE7941820240954C70|ctaB]-[gene|72D5442C0EF3B404F7B615366E357B68C863CEB6|ctaC]-[gene|20D1174554A03EECE233A1A045F6DF83AF799959|ctaD]-[gene|9DF8423F1D63ED3928B2818F58BC3DECCDBB1DDB|ctaE]-[gene|28E5AF86CE49D7B0ECBFAF9ED5C1FC65D9F810EA|ctaF]-[gene|8C16E115CB59A74C24954BFCDE112720BA09D5EA|ctaG]
description
[Pubmed|9829923]
regulation
expressed under anaerobic conditions ([protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]) [Pubmed|9829923]
regulatory mechanism
[protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]: activation, [Pubmed|9829923], in [regulon|protein:1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD regulon]
[protein|5872812AB61E92E2944E926915EB7FEE71BFA6D5|abh]: repression, synergistic repression with [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB], in [regulon|protein:5872812AB61E92E2944E926915EB7FEE71BFA6D5|abh regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, synergistic repression with [protein|5872812AB61E92E2944E926915EB7FEE71BFA6D5|abh], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
Biological materials
Mutant
BKE14910 ([gene|9DF8423F1D63ED3928B2818F58BC3DECCDBB1DDB|ctaE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGTGAATTTTTCTTGAACTT, downstream forward: _UP4_TTAATGGGGATGGTGGGATA
BKK14910 ([gene|9DF8423F1D63ED3928B2818F58BC3DECCDBB1DDB|ctaE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGTGAATTTTTCTTGAACTT, downstream forward: _UP4_TTAATGGGGATGGTGGGATA
References
Reviews
Original Publications
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Time of last update: 2024-12-30 23:48:15
Author of last update: Jstuelk