sivC
168
inhibitor of entry into sporulation via [protein|2111AC1AE49D1006E10DC127BF5B7A0327DE94A7|kinB] or [protein|A656321846B2E0D1F39B528E2D8B8E620CCD1148|kinC]
locus
BSU_15960
Molecular weight
17.60 kDa
pI
8.61
function
control of entry into sporulation via the phosphorelay
product
inhibitor of entry into sporulation
essential
no
synonyms
sivC, ylqB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
1,671,166 1,671,651
The protein
Catalyzed reaction/ biological activity
inhibits [protein|2111AC1AE49D1006E10DC127BF5B7A0327DE94A7|kinB] or [protein|A656321846B2E0D1F39B528E2D8B8E620CCD1148|kinC] activity [Pubmed|23335417]
Structure
[AF|O31737]
[wiki|Localization]
extracellular (signal peptide) [Pubmed|18957862]
Expression and Regulation
Operons
genes
[gene|9D320646C56FA83962BFBE73E22F2BCF2F0788B1|sivC]
description
[Pubmed|15033535]
regulation
repressed by casamino acids [Pubmed|12107147]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|18840696], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
sigma factors
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD]: sigma factor, [Pubmed|15033535], in [regulon|protein:7024E4162A6D827069F882FDEACA696EBC05DD40|sigD regulon]
Biological materials
Mutant
MGNA-B140 (ylqB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1139 NBRP B. subtilis, Japan]
BKE15960 (''[gene|9D320646C56FA83962BFBE73E22F2BCF2F0788B1|sivC]''::''erm'', available in the BGSC and in [wiki|Jörg Stülke]'s lab) [pubmed|28189581]
GP1823(''[gene|9D320646C56FA83962BFBE73E22F2BCF2F0788B1|sivC]''::''erm'', available in [wiki|Jörg Stülke]'s lab)
BKE15960 ([gene|9D320646C56FA83962BFBE73E22F2BCF2F0788B1|sivC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAAAATCCTCCTTAAAA, downstream forward: _UP4_TAAAAAAGAAAAAGGCCCCA
BKK15960 ([gene|9D320646C56FA83962BFBE73E22F2BCF2F0788B1|sivC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAAAATCCTCCTTAAAA, downstream forward: _UP4_TAAAAAAGAAAAAGGCCCCA
References
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Time of last update: 2025-04-06 02:33:32
Author of last update: Jstuelk