ldcB

ldcB
168

LD-carboxypeptidase, releases D-Ala from the cell wall

locus
BSU_19620
Molecular weight
30.70 kDa
pI
5.84
Protein length
Gene length
function
cell wall synthesis
product
LD-carboxypeptidase
essential
no
ec
null
synonyms
ldcB, yodJ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1876 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,134,566  2,135,387
The protein
Catalyzed reaction/ biological activity
trimming of cell wall peptides (tetrapeptides to tripeptides) wit concomitant release of D-ala [Pubmed|24909784]
Protein family
peptidase M15B family (single member, according to UniProt)
[wiki|Cofactors]
Zn2+ [Pubmed|24909784]
Structure
[PDB|4OX3] [Pubmed|24909784]
[AF|O34866]
[wiki|Localization]
extracellular (signal peptide) [Pubmed|18957862]
Expression and Regulation
Operons
genes
[gene|3075327DBE55C4F628171AEE248CAED5870693FA|deoD]-[gene|9A22825FD67B6A205807433D0B4908F86E5AB343|ldcB]
description
[Pubmed|22383849]
Open in new tab

[gene|3075327DBE55C4F628171AEE248CAED5870693FA|deoD]→[gene|9A22825FD67B6A205807433D0B4908F86E5AB343|ldcB]

2024-10-10 08:23:22

ghost

73

66be4dd285efbcad285fd8f6ed4315cd638475ae

FA3379F0B03A2DB25E37DAF87C26DE840FC23E8F

Biological materials
Mutant
MGNA-B439 (yodJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1438 NBRP B. subtilis, Japan]
BKE19620 ([gene|9A22825FD67B6A205807433D0B4908F86E5AB343|ldcB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE19620 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTACATTACCTTCCTT,  downstream forward: _UP4_TAAAATGAAAAGCCCGCTTA
BKK19620 ([gene|9A22825FD67B6A205807433D0B4908F86E5AB343|ldcB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK19620 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTACATTACCTTCCTT,  downstream forward: _UP4_TAAAATGAAAAGCCCGCTTA
References
18957862,24909784,22383849,21378199

9A22825FD67B6A205807433D0B4908F86E5AB343

Page visits: 3843

Time of last update: 2024-10-10 15:29:56

Author of last update: Melvin.boenninger