phrE
168
response regulator aspartate phosphatase (RapE) regulator, control of the phosphorelay
locus
BSU_25840
Molecular weight
4.72 kDa
pI
8.86
function
control of sporulation initiation
product
phosphatase (RapE) regulator
essential
no
ec
null
synonyms
phrE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
2,660,330 2,660,464
The protein
Protein family
[wiki|phr family] (according to UniProt)
Structure
[AF|O32025]
Expression and Regulation
Operons
genes
[gene|997434F9679B3A2F8D2453D0C3BAB24F5BB90922|phrE]
description
[Pubmed|11466295]
regulation
repressed by glucose (10-fold) ([protein|search|CcpA]) [Pubmed|12850135]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY]: repression, [Pubmed|12618455], in [regulon|protein:90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY regulon]
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
[protein|7832489F11F606BCF637EC23BAAB41AD10237EBB|comA]: activation, in [regulon|protein:7832489F11F606BCF637EC23BAAB41AD10237EBB|comA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|11466295], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|sigH]: sigma factor, [Pubmed|11466295], in [regulon|protein:DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|sigH regulon]
genes
[gene|8B8646DF7F437D8DB299A77BA937DC6FC082102F|rapE]-[gene|997434F9679B3A2F8D2453D0C3BAB24F5BB90922|phrE]
description
[Pubmed|11466295,10629174]
regulation
repressed by glucose (10-fold) ([protein|search|CcpA]) [Pubmed|12850135]
regulatory mechanism
[protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY]: repression, [Pubmed|23569278,12618455], in [regulon|protein:90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY regulon]
[protein|7832489F11F606BCF637EC23BAAB41AD10237EBB|comA]: activation, in [regulon|protein:7832489F11F606BCF637EC23BAAB41AD10237EBB|comA regulon]
Biological materials
Mutant
BKE25840 ([gene|997434F9679B3A2F8D2453D0C3BAB24F5BB90922|phrE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE25840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AACGGCGGATAAACTGATAA, downstream forward: _UP4_TAATTCGATAAACAACATTA
BKK25840 ([gene|997434F9679B3A2F8D2453D0C3BAB24F5BB90922|phrE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK25840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AACGGCGGATAAACTGATAA, downstream forward: _UP4_TAATTCGATAAACAACATTA
References
Reviews
Original Publications
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Time of last update: 2025-04-01 20:32:28
Author of last update: Jstuelk