nucA

nucA
168

membrane-associated nuclease, catalyzes DNA cleavage during transformation

locus
BSU_03430
Molecular weight
16.12 kDa
pI
4.68
Protein length
Gene length
function
genetic transformation, DNA uptake
product
membrane-associated nuclease
essential
no
synonyms
nucA, comI

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
372,154  372,597
The protein
Structure
[PDB|5OMT] ([protein|search|NucB ]from B. licheniformis, 64% identity, aa 40 - 147) [pubmed|29165717]
[AF|P12667]
[wiki|Localization]
integral membrane protein [Pubmed|11359569]
Expression and Regulation
Operons
genes
[gene|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]-[gene|3A54C644DD1CCA5C08CB9C5CD648D44889E68D23|nin]
description
[Pubmed|11359569]
regulatory mechanism
[protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK]: activation, [Pubmed|7746143], in [regulon|protein:08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK regulon]
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[gene|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]→[gene|3A54C644DD1CCA5C08CB9C5CD648D44889E68D23|nin]

2024-12-17 05:50:38

ghost

92

3d65de19fb3917bf958be1ea102db63bbed32b9e

E1F6E1DEA056BA36F3673F7E5D4426F5F47FF7A0

Biological materials
Mutant
BKE03430 ([gene|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03430 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GATGTTCACCTCCCGCTTTT,  downstream forward: _UP4_TAAACAGTACATAGAGGAGG
BKK03430 ([gene|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03430 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GATGTTCACCTCCCGCTTTT,  downstream forward: _UP4_TAAACAGTACATAGAGGAGG
References
11814663,11359569,7746143,29165717,34126763,39375363

99581CC6AFFA2D1392748B4D9C99DEF8B7601F75

Page visits: 6771

Time of last update: 2024-12-21 22:57:07

Author of last update: Jstuelk