nucA
168
membrane-associated nuclease, catalyzes DNA cleavage during transformation
locus
BSU_03430
Molecular weight
16.12 kDa
pI
4.68
function
genetic transformation, DNA uptake
product
membrane-associated nuclease
essential
no
synonyms
nucA, comI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
372,154 372,597
The protein
Structure
[PDB|5OMT] ([protein|search|NucB ]from B. licheniformis, 64% identity, aa 40 - 147) [pubmed|29165717]
[AF|P12667]
[wiki|Localization]
integral membrane protein [Pubmed|11359569]
Expression and Regulation
Operons
genes
[gene|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]-[gene|3A54C644DD1CCA5C08CB9C5CD648D44889E68D23|nin]
description
[Pubmed|11359569]
regulatory mechanism
[protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK]: activation, [Pubmed|7746143], in [regulon|protein:08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK regulon]
Biological materials
Mutant
BKE03430 ([gene|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGTTCACCTCCCGCTTTT, downstream forward: _UP4_TAAACAGTACATAGAGGAGG
BKK03430 ([gene|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGTTCACCTCCCGCTTTT, downstream forward: _UP4_TAAACAGTACATAGAGGAGG
References
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Time of last update: 2024-12-21 22:57:07
Author of last update: Jstuelk