pucB
168
xanthine dehydrogenase
locus
BSU_32500
Molecular weight
20.91 kDa
pI
7.92
function
purine utilization
product
xanthine dehydrogenase
essential
no
synonyms
pucB, yurE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2068 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,339,331 3,339,948
The protein
Structure
[PDB|2WAW] (from Mycobacterium tuberculosis, 27% identity)
[AF|O32146]
Expression and Regulation
Operons
genes
[gene|C9370B221117B89A1134B413748D39505C2E1DA8|pucA]-[gene|99428BD0B1A8E91F4B028ACF8AB51B235DDB4F11|pucB]-[gene|D0F00ACF5AAD9E9418033F5B47527C4D50007F18|pucC]-[gene|B65E4B340961332ED0ACC7FD957351256F708F60|pucD]-[gene|6855CC156FCB4C4A16AFD6ADE18F3FFC82B61843|pucE]
description
[Pubmed|12823818]
regulation
induced in the presence of purine nucleotides (effector: allantoin) ([protein|search|PucR]) [Pubmed|12029039]
regulatory mechanism
[protein|52C1601482C26400A524E880334BB801F832D6ED|pucR]: activation, [Pubmed|12029039], in [regulon|protein:52C1601482C26400A524E880334BB801F832D6ED|pucR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|12029039], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-A941 (yurE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/941 NBRP B. subtilis, Japan]
BKE32500 ([gene|99428BD0B1A8E91F4B028ACF8AB51B235DDB4F11|pucB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32500 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCTCATACAACCGCCACCCG, downstream forward: _UP4_TCTTGAACGGCCAAGTGACA
BKK32500 ([gene|99428BD0B1A8E91F4B028ACF8AB51B235DDB4F11|pucB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32500 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCTCATACAACCGCCACCCG, downstream forward: _UP4_TCTTGAACGGCCAAGTGACA
References
Page visits: 1727
Time of last update: 2024-11-14 12:48:35
Author of last update: Jstuelk