comER
168
control of biofilm formation and sporulation via the phosphorelay
locus
BSU_25600
Molecular weight
30.09 kDa
pI
6.18
function
control of biofilm formation and sporulation via the phosphorelay
product
putative pyrroline-5-carboxylate reductase
essential
no
synonyms
comER, comED
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0345 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,641,214 2,642,035
Phenotypes of a mutant
defects in [wiki|biofilm formation] and a delay in [wiki|sporulation] [Pubmed|27446060]
The protein
Catalyzed reaction/ biological activity
the protein does not have significant pyrroline-5-carboxylate reductase activity and does not contribute to proline biosynthesis [pubmed|28824574,11418582]
Protein family
[wiki|pyrroline-5-carboxylate reductase family] [pubmed|28824574]
Structure
[AF|P39696]
Additional information
forms monomers [pubmed|28824574]
Expression and Regulation
Operons
genes
[gene|9840EA950FD7F4D18FDD0AB9AC65491E9F8BCC1C|comER]
description
[Pubmed|7968523]
regulation
repressed by casamino acids [Pubmed|12107147]
additional information
An [wiki|ncRNA] is predicted for '[protein|search|comER]' [PubMed|20525796]
Biological materials
Mutant
BKE25600 ([gene|9840EA950FD7F4D18FDD0AB9AC65491E9F8BCC1C|comER]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE25600 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGGTTTCCCCTCCTTTG, downstream forward: _UP4_TAGACGAGTATGTCATACGT
BKK25600 ([gene|9840EA950FD7F4D18FDD0AB9AC65491E9F8BCC1C|comER]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK25600 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGGTTTCCCCTCCTTTG, downstream forward: _UP4_TAGACGAGTATGTCATACGT
References
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Time of last update: 2024-12-21 20:54:55
Author of last update: Jstuelk