rsbRD
168
probably part of the [wiki|stressosome], negative regulator of [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB] activity
locus
BSU_24760
Molecular weight
31.66 kDa
pI
5.09
function
control of [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB] activity
product
[protein|621357D1FB6AC1B0499732EFE226F982B26CE34E|rsbR] paralog
essential
no
synonyms
rsbRD, yqhA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1366 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,562,966 2,563,802
The protein
[wiki|Domains]
[wiki|STAS domain] (aa 160-271) (according to UniProt)
Structure
[AF|P54504]
Modification
phosphorylation on Thr-181 by [protein|ADC52A22950736A0435AEEEC43F7407878786A81|rsbT] [Pubmed|21362065]
Paralogous protein(s)
[protein|F53C527995909A1CFA72C7BF919DD10EE175C6D7|rsbRB], [protein|5EEEDE60CE9E5CDAEBAB0E03AABDF1DF62F1F002|rsbRC], [protein|621357D1FB6AC1B0499732EFE226F982B26CE34E|rsbR], [protein|6C5397BA5839E4DB25B370B39B6DA702147DA8B7|ytvA]
Expression and Regulation
Operons
genes
[gene|979D7A45EAD97C99015029400A85795061BAA367|rsbRD]
description
(according to [http://dbtbs.hgc.jp/COG/prom/yqhA.html DBTBS]) null
regulation
expressed under stress conditions ([protein|search|SigB]) [Pubmed|10482513,20019076]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|10482513], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
MGNA-C475 (yqhA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2473 NBRP B. subtilis, Japan]
BKE24760 ([gene|979D7A45EAD97C99015029400A85795061BAA367|rsbRD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTAATGAGTTACCTCC, downstream forward: _UP4_TGATGCCTTTGCCATGTTTA
BKK24760 ([gene|979D7A45EAD97C99015029400A85795061BAA367|rsbRD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTAATGAGTTACCTCC, downstream forward: _UP4_TGATGCCTTTGCCATGTTTA
References
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Time of last update: 2024-12-20 02:40:14
Author of last update: Jstuelk