oxdC
168
oxalate decarboxylase
locus
BSU_33240
Molecular weight
43.41 kDa
pI
5.1
function
unknown
product
oxalate decarboxylase
essential
no
ec
4.1.1.2
synonyms
oxdC, yvrK
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2140 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,410,466 3,411,623
The protein
Catalyzed reaction/ biological activity
H+ + oxalate --> CO2 + formate (according to UniProt)
[wiki|Cofactors]
requires two Mn(II) centers for activity [Pubmed|24444454,19473032]
Structure
[PDB|1L3J] [pubmed|14871895]
[AF|O34714]
Modification
phosphorylated on Arg-12 [Pubmed|22517742]
Paralogous protein(s)
[protein|1568DD457FDD482B3C14954A95F62BE338CBD15D|oxdD]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC]-[gene|07C35D58F6AF97F8E6BB75CF8E8B811BAFAB201B|rsiO]
description
[Pubmed|19047353]
regulation
induced by acidic growth conditions [Pubmed|19047353]
sigma factors
[protein|6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO]: sigma factor, [Pubmed|19047353], in [regulon|protein:6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO regulon]
[protein|AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA]: sigma factor, in [regulon|protein:AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA regulon]
Biological materials
Mutant
MGNA-B053 (yvrK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1052 NBRP B. subtilis, Japan]
BKE33240 ([gene|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAAATGTTTCCTCCTTA, downstream forward: _UP4_TAAAAGACTTGCGGCTTGCA
BKK33240 ([gene|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAAATGTTTCCTCCTTA, downstream forward: _UP4_TAAAAGACTTGCGGCTTGCA
labs
[wiki|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
References
Reviews
Original Publications
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Time of last update: 2024-10-04 19:29:40
Author of last update: Jstuelk