oxdC

oxdC
168

oxalate decarboxylase

locus
BSU_33240
Molecular weight
43.41 kDa
pI
5.1
Protein length
385 aaSequenceBlast
Gene length
1158 bpSequenceBlast
function
unknown
product
oxalate decarboxylase
essential
no
ec
4.1.1.2
synonyms
oxdC, yvrK
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2140 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,410,466  3,411,623
The protein
Catalyzed reaction/ biological activity
H+ + oxalate --> CO2 + formate (according to UniProt)
[wiki|Cofactors]
requires two Mn(II) centers for activity [Pubmed|24444454,19473032]
Structure
[PDB|1L3J] [pubmed|14871895]
[AF|O34714]
Modification
phosphorylated on Arg-12 [Pubmed|22517742]
Paralogous protein(s)
[protein|1568DD457FDD482B3C14954A95F62BE338CBD15D|oxdD]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC]-[gene|07C35D58F6AF97F8E6BB75CF8E8B811BAFAB201B|rsiO]
description
[Pubmed|19047353]
regulation
induced by acidic growth conditions [Pubmed|19047353]
sigma factors
[protein|6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO]: sigma factor, [Pubmed|19047353], in [regulon|protein:6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO regulon]
[protein|AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA]: sigma factor, in [regulon|protein:AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA regulon]
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[gene|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC]→[gene|07C35D58F6AF97F8E6BB75CF8E8B811BAFAB201B|rsiO]

2024-12-22 06:14:53

ghost

74

45fe15923d4d9abe55bc1d08f5e4cf8ec93e3aab

C45787333A7E680B1778F2A70AF5C84FB28484FA

Biological materials
Mutant
MGNA-B053 (yvrK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1052 NBRP B. subtilis, Japan]
BKE33240 ([gene|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33240 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAAATGTTTCCTCCTTA,  downstream forward: _UP4_TAAAAGACTTGCGGCTTGCA
BKK33240 ([gene|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33240 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAAATGTTTCCTCCTTA,  downstream forward: _UP4_TAAAAGACTTGCGGCTTGCA
labs
[wiki|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
References
Reviews
20464388
Original Publications
12056897,18573182,17269748,14871895,10960116,19047353,19473032,11546787,15583401,21264418,21782782,22404040,23734819,25526893,21277974,22517742,24444454,25186982,26641915,26744902,27797181,14871895,29620872,30806021,34097877,36482787,39339409

9793E952C985BA268AC28C907900A03F4E8A3253

Page visits: 3675

Time of last update: 2024-12-21 07:25:44

Author of last update: Jstuelk