yitD
168
phosphosulfolactate synthase
locus
BSU_10950
Molecular weight
28.21 kDa
pI
4.38
function
biosynthesis of L-sulfolactate
product
phosphosulfolactate synthase
essential
no
ec
4.4.1.19
synonyms
yitD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1809 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,173,333 1,174,091
The protein
Catalyzed reaction/ biological activity
(2R)-O-phospho-3-sulfolactate --> H+ + phosphoenolpyruvate + sulfite (according to UniProt)
Protein family
phosphosulfolactate synthase family (single member, according to UniProt)
Structure
[PDB|1U83]
[AF|O06739]
Expression and Regulation
Operons
genes
[gene|FA7147930DA90604BE2B4837A8A4393F72498AB1|yitC]-[gene|97156E7227E298B0DECC9AAC1411D0DAF3420C29|yitD]
description
[Pubmed|22383849]
regulation
expressed during [wiki|sporulation] in the mother cell ([protein|search|SigE], [protein|search|SigK]) [Pubmed|15699190,15383836]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15383836], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,15383836], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
Biological materials
Mutant
MGNA-B178 (yitD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1177 NBRP B. subtilis, Japan]
BKE10950 ([gene|97156E7227E298B0DECC9AAC1411D0DAF3420C29|yitD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10950 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGGCAATTCTAGTGAAAAAT, downstream forward: _UP4_TAAAATAGCGGCTGCGGGGC
BKK10950 ([gene|97156E7227E298B0DECC9AAC1411D0DAF3420C29|yitD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10950 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGGCAATTCTAGTGAAAAAT, downstream forward: _UP4_TAAAATAGCGGCTGCGGGGC
References
Page visits: 1964
Time of last update: 2024-12-21 11:33:09
Author of last update: Melvin.boenninger