spoVB
168
MurJ family lipid II flippase, spore cortex peptidoglycan synthesis
locus
BSU_27670
Molecular weight
55.91 kDa
pI
10.19
function
spore cortex peptidoglycan synthesis
product
sporulation-specific MurJ family lipid II flippase
essential
no
synonyms
spoVB, spoIIIF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5841 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,829,564 2,831,120
The protein
Protein family
[wiki|Polysaccharide synthase family] (according to UniProt)
[wiki|MOP exporter family]
Structure
[AF|Q00758]
Paralogous protein(s)
[protein|D6B1837075ECBEE1FEAC704DDB6795336092897F|yabM], [protein|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|murJ], [protein|34A5CD28A3DBCB10B4E1C82E50143FA73B553919|ykvU]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]-[gene|C52461A2FE856C94E0D0701FB7412368404FC83B|yrzE]
description
[pubmed|22383849]
regulation
expressed early during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE], [wiki|SpoIIID]) [Pubmed|1744050,15383836]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: repression, [pubmed|15383836], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [pubmed|1744050], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
BKE27670 ([gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTACCCCCTGCCTTC, downstream forward: _UP4_GGACGGTTGATCATCCGATA
BKK27670 ([gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTACCCCCTGCCTTC, downstream forward: _UP4_GGACGGTTGATCATCCGATA
References
Reviews
Original Publications
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Time of last update: 2024-10-09 06:36:45
Author of last update: Jstuelk