yhfW
168
similar to Rieske 2Fe-2S iron-sulfur protein
locus
BSU_10390
Molecular weight
56.94 kDa
pI
5.66
function
unknown
product
unknown
essential
no
synonyms
yhfW
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0723 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,114,057 1,115,586
Phenotypes of a mutant
reduced transfomation efficiency [pubmed|32249531]
reduced amounts of citric acid cycle intermediates [pubmed|32249531]
The protein
[wiki|Domains]
Rieske domain (aa 423-509) (according to UniProt)
[wiki|Cofactors]
Fe-S cluster [pubmed|29292548]
Structure
[PDB|4P9S] (dimethylglycine dehydrogenase from Rattus norvegicus, corresponds to aa 22 ... 396, 25% identity) [pubmed|24858690]
[AF|O07622]
Expression and Regulation
Operons
genes
[gene|96136B1EDFAA1A34ED012CB5BA1DDFB8A95FB4A1|yhfW]
description
[Pubmed|15033535]
regulation
expressed during sporulation in the forespore ([protein|search|SigF]) [Pubmed|15699190]
sigma factors
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|15699190], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
Biological materials
Mutant
MGNA-A716 (yhfW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/716 NBRP B. subtilis, Japan]
BKE10390 ([gene|96136B1EDFAA1A34ED012CB5BA1DDFB8A95FB4A1|yhfW]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGCCGTTATACCTCCAAT, downstream forward: _UP4_TAAACCGTTCATTTTAATGA
BKK10390 ([gene|96136B1EDFAA1A34ED012CB5BA1DDFB8A95FB4A1|yhfW]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGCCGTTATACCTCCAAT, downstream forward: _UP4_TAAACCGTTCATTTTAATGA
References
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Time of last update: 2024-12-28 12:55:18
Author of last update: Jstuelk