pghZ
168
phage-derived gamma polyglutamic acid hydrolase
locus
BSU_20460
Molecular weight
30.21 kDa
pI
8.59
function
polyglutamic acid degradation
product
phage-derived gamma polyglutamic acid hydrolase
essential
no
synonyms
pghZ, yoqZ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4195 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,189,961 2,190,785
The protein
Catalyzed reaction/ biological activity
hydrolysis of polyglutamic acid [Pubmed|26158264]
Protein family
[wiki|UPF0714 family] (according to UniProt)
[wiki|Domains]
DUF867 [http://pfam.xfam.org/family/PF05908 x], [[gamma-PGA hydrolase domain]] [Pubmed|26158264]
Structure
[PDB|3A9L] (from B. subtilis phage NIT1, 43% identity) [pubmed|22105902]
[AF|O31913]
Paralogous protein(s)
[protein|BA7D1D112E934B68073DFC1F76248ED6157240E3|pghB], [protein|DF95DED9A6E2160C151D7664C951B198EEA225E8|pghC], [protein|FD862CE6C4A37B17714F8F8687B3266D43EF5F63|pghL]
Biological materials
Mutant
BKE20460 ([gene|8F9DCD77660706E4D25CD7875C014F6A2B5D8123|pghZ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE20460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATCAACAACTCTCCTTAA, downstream forward: _UP4_TATTGTATGGCTGGTGTAGC
BKK20460 ([gene|8F9DCD77660706E4D25CD7875C014F6A2B5D8123|pghZ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK20460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATCAACAACTCTCCTTAA, downstream forward: _UP4_TATTGTATGGCTGGTGTAGC
References
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Time of last update: 2024-10-10 07:01:16
Author of last update: Melvin.boenninger