cotP
168
inner spore coat protein
locus
BSU_05550
Molecular weight
16.91 kDa
pI
4.56
function
resistance of the spore
product
inner spore coat protein
essential
no
synonyms
cotP, ydfT
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0071 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
601,741 602,172
The protein
Protein family
[wiki|small heat shock protein (Hsp20) family] (according to UniProt)
[wiki|Domains]
sHSP domain (aa 34-143) (according to UniProt)
Structure
[AF|P96698]
[wiki|Localization]
inner spore coat, localization depends on [protein|CEBEC9CECCF445C40D793E61A2CD23175631A473|safA] [Pubmed|22171814]
Expression and Regulation
Operons
genes
[gene|68E585F6670539982E8E8032337DA2043C67FCC4|ydgB]-[gene|483587EB658850D786C3C95C02D419994FCC9F45|ydgA]-[gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]
description
[Pubmed|22383849]
regulation
expressed during sporulation ([protein|6FAD8804AA32B84819DDE57C0AF63F208FB9FFD1|sigKC]) [Pubmed|15699190]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: repression, [Pubmed|9068633], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
Biological materials
Mutant
MGNA-C172 (ydfT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2170 NBRP B. subtilis, Japan]
BKE05550 ([gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAGATTCTCCTTAAA, downstream forward: _UP4_GGGCTTTAAGATTGATTGTT
BKK05550 ([gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAGATTCTCCTTAAA, downstream forward: _UP4_GGGCTTTAAGATTGATTGTT
References
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Time of last update: 2024-12-18 21:25:19
Author of last update: Melvin.boenninger