nicK
168
DNA relaxase, similar to transposon protein
locus
BSU_04870
Molecular weight
40.78 kDa
pI
5.13
function
conjugation of ICE BS1
product
DNA relaxase, similar to transposon protein
essential
no
ec
null
synonyms
nicK, ydcR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2946 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
534,773 535,831
The protein
Protein family
plasmid replication initiation factor family (single member, according to UniProt)
Structure
[PDB|4CIJ] (from Geobacillus stearothermophilus, corresponds to aa 26 ... 289, 33% identity) [pubmed|26792891]
[AF|P96635]
Expression and Regulation
Operons
genes
[gene|EE2A4068CBD7A2F852E582E2EDA4148381F1CD61|xis]-[gene|2227923C603B290AB276238F789D71584FB07DF3|ydzL]-[gene|34451538F10B4ABCFC8A236C8C905A20D989EBCF|devI]-[gene|C042792D9A643DCFF4A851EFECA3CF2C31E1EDAF|ydcP]-[gene|4BCAA5939CB7F0DF23495BC92C9EF0A0149296A0|ydcQ]-[gene|8E179976C35FE09F92A191D00E497ED4BF28F571|nicK]-[gene|886B2132717BA4C72433ABE351C5791C9DE1432A|S172]-[gene|1699CFBF5400CAF43C6DAE8ADCCE5A360B31F2E9|ramS]-[gene|9D4918852A1856B1CDD72D49AEA75E51A8602BB6|ramT]-[gene|62CEABA069CA2970F22B7E0C369D540A2A027A8D|ramA]-[gene|A0AFD543582D2FE8B1139CF69B7B1F7FF0F80265|conB]-[gene|F273A8817E66B44D58FC2BCB6576A30D8616B750|conC]-[gene|F1F898D7A9FDF78D2E5E8F3BF605E0F735D0542A|conD]-[gene|D20F724D8C3E8C758A9FADF133CD43F066BD8D48|conE]-[gene|B3A07E2A61151C33B7C65D1BC58B97BFDB76852D|yddF]-[gene|3356A43B83E2D4D66098F17A751F0912C1553398|conG]-[gene|8D9D81E05BAA8697F002BB1B8DBC5ABBA557353F|cwlT]-[gene|2E4FF80C857B3F40BA835814EC40D6562721AEFE|yddI]-[gene|2FB1C9435AE924F8E450AFA81F800196A871F2D0|yddJ]
description
[pubmed|22383849]
regulatory mechanism
[protein|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]: repression, [Pubmed|17511812], in [regulon|protein:DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR regulon]
Biological materials
Mutant
BKE04870 ([gene|8E179976C35FE09F92A191D00E497ED4BF28F571|nicK]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GCTCATCCATTCGCTTCGCT, downstream forward: _UP4_TAAAACCAAGCTGCTAAACC
BKK04870 ([gene|8E179976C35FE09F92A191D00E497ED4BF28F571|nicK]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GCTCATCCATTCGCTTCGCT, downstream forward: _UP4_TAAAACCAAGCTGCTAAACC
References
Reviews
Original Publications
Page visits: 2070
Time of last update: 2025-03-18 08:16:57
Author of last update: Jstuelk