rapE

rapE
168

response regulator aspartate phosphatase, dephosphorylates [protein|9896B99346B0D3F6D57F57377DB253B46135A37A|spo0F]-P, control of the [wiki|phosphorelay]

locus
BSU_25830
Molecular weight
44.40 kDa
pI
7.31
Protein length
375 aaSequenceBlast
Gene length
1128 bpSequenceBlast
function
control of [wiki|sporulation] initiation
product
response regulator aspartate phosphatase
essential
no
synonyms
rapE, yqcH
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
2,659,213  2,660,340
The protein
Protein family
[wiki|RAP family] (according to UniProt)
[wiki|Domains]
six [wiki|TPR repeat|tetratrichopeptide repeats] (according to UniProt)
Structure
[PDB|4I9E] ([protein|1F860F4E66A3D503D5A97F17D4AB0504BEFE7F9D|rapF], 38% identity) [pubmed|23526880]
[AF|P45943]
Expression and Regulation
Operons
genes
[gene|8B8646DF7F437D8DB299A77BA937DC6FC082102F|rapE]-[gene|997434F9679B3A2F8D2453D0C3BAB24F5BB90922|phrE]
description
[Pubmed|11466295,10629174]
regulation
repressed by glucose (10-fold) ([protein|search|CcpA]) [Pubmed|12850135]
regulatory mechanism
[protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY]: repression, [Pubmed|23569278,12618455], in [regulon|protein:90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY regulon]
[protein|7832489F11F606BCF637EC23BAAB41AD10237EBB|comA]: activation, in [regulon|protein:7832489F11F606BCF637EC23BAAB41AD10237EBB|comA regulon]
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[gene|8B8646DF7F437D8DB299A77BA937DC6FC082102F|rapE]→[gene|997434F9679B3A2F8D2453D0C3BAB24F5BB90922|phrE]

2024-10-10 18:28:16

ghost

70

f608cde1e59e85e18714813f7f7758010526367d

952AED7D01C486511F8A9AB8B0D3EDEAA707B8AA

Biological materials
Mutant
BKE25830 ([gene|8B8646DF7F437D8DB299A77BA937DC6FC082102F|rapE]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE25830 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGATATTCACCCTTCCCT,  downstream forward: _UP4_CAAATATCGAAAGGGGAATG
BKK25830 ([gene|8B8646DF7F437D8DB299A77BA937DC6FC082102F|rapE]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK25830 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGATATTCACCCTTCCCT,  downstream forward: _UP4_CAAATATCGAAAGGGGAATG
References
Reviews
37042030
Original Publications
12618455,11466295,10629174,23569278,25225273,23526880

8B8646DF7F437D8DB299A77BA937DC6FC082102F

Page visits: 4099

Time of last update: 2024-10-11 06:23:51

Author of last update: Jstuelk