yxdL

yxdL
168

[wiki|ABC transporter] (ATP-binding protein)

locus
BSU_39640
Molecular weight
28.57 kDa
pI
7.36
Protein length
Gene length
function
export of toxic peptides
product
[wiki|ABC transporter] (ATP-binding protein)
essential
no
synonyms
yxdL, apeA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1136 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,070,393  4,071,166
The protein
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transporter domain] (aa 5-243) (according to UniProt)
Structure
[PDB|1L2T] (from Methanocaldococcus jannaschii, 43% identity) [pubmed|12150914]
[AF|P42423]
Paralogous protein(s)
[protein|8BF7EB539B53D75BD30BD30ABF27106D6A0B030B|ftsE], [protein|8E0DE8FE7E9C12495C4DCADA74D838FED088867D|bceA], [protein|FE3A01BEA974C5E32C68DC600C800E5EF101B34F|yknY], [protein|4FE6A51A0D9BBBF574EA2EF18B95B5BFC0A64CCB|ytrE], [protein|0F8048267EC038D8CF673317D969BA27735473A7|yvrO], [protein|464DD1855E6B3195EE242637612A16C73FF32FC0|psdA]
[wiki|Localization]
plasma membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|8B4267532B9788AEB5EF39E2695C1FDA494C7055|yxdL]-[gene|4423383A3F6DAFDFA210F4BEEF7D8CBEC674DCEA|yxdM]-[gene|6D9153BA698101C3EE1CD68B76419ECD300740F8|yxeA]
description
[Pubmed|15289557]
regulation
induced by a cationic antimicrobial peptide, LL-37 ([protein|search|YxdJ]) [Pubmed| 21078927]
regulatory mechanism
[protein|F3C5505E311E6DDABAFA87899F28CF6596CDBA63|yxdJ]: activation, [Pubmed|15289557], in [regulon|protein:F3C5505E311E6DDABAFA87899F28CF6596CDBA63|yxdJ regulon]
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[gene|8B4267532B9788AEB5EF39E2695C1FDA494C7055|yxdL]→[gene|6D9153BA698101C3EE1CD68B76419ECD300740F8|yxeA]

2024-10-01 14:50:42

ghost

76

1ab86e0dc85847b3c96c257da5ca800b574323a8

8B1742B0EB6B6B4B987D10A9F8126850382B12E8

Biological materials
Mutant
MGNA-B704 (yxdL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1703 NBRP B. subtilis, Japan]
BKE39640 ([gene|8B4267532B9788AEB5EF39E2695C1FDA494C7055|yxdL]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE39640 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAAAATCCTCCTTATGG,  downstream forward: _UP4_CTGTCTATGCTGGGGGGAAA
BKK39640 ([gene|8B4267532B9788AEB5EF39E2695C1FDA494C7055|yxdL]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK39640 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAAAATCCTCCTTATGG,  downstream forward: _UP4_CTGTCTATGCTGGGGGGAAA
References
Reviews
38869304
Original Publications
17600057,10092453,15289557,21283517

8B4267532B9788AEB5EF39E2695C1FDA494C7055

Page visits: 3591

Time of last update: 2024-10-12 03:30:50

Author of last update: Jstuelk