yrkQ
168
two-component sensor kinase
locus
BSU_26420
Molecular weight
49.56 kDa
pI
5.16
function
unknown
product
two-component sensor kinase
essential
no
synonyms
yrkQ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2205 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,703,150 2,704,448
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of [protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)
[wiki|Domains]
two transmembrane segments, C-terminal histidine phosphotransferase domain
[wiki|HAMP domain] (aa 167-219) (according to UniProt)
[wiki|Histidine kinase domain] (aa 234-432) (according to UniProt)
Structure
[AF|P54444]
Modification
autophosphorylation on a His residue
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]-[gene|8A38FEFAA0FF91D989B77D40CBB3741902DC9D67|yrkQ]-[gene|E0DF6DE230AD0B632EEC0A1FB11EB32E59BD573E|yrkR]
description
[Pubmed|18175906]
regulatory mechanism
[protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]: activation, [Pubmed|18175906], in [regulon|protein:1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP regulon]
Biological materials
Mutant
MGNA-C423 (yrkQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2421 NBRP B. subtilis, Japan]
BKE26420 ([gene|8A38FEFAA0FF91D989B77D40CBB3741902DC9D67|yrkQ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE26420 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGCCAGTTTTTTGGTTAGCG, downstream forward: _UP4_TAGGCTGAGAATAAAAACCA
BKK26420 ([gene|8A38FEFAA0FF91D989B77D40CBB3741902DC9D67|yrkQ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK26420 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGCCAGTTTTTTGGTTAGCG, downstream forward: _UP4_TAGGCTGAGAATAAAAACCA
References
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Time of last update: 2024-12-20 08:59:59
Author of last update: Melvin.boenninger