kdgR

kdgR
168

transcriptional repressor of the pectin utilization operon ([wiki|LacI family])

locus
BSU_22120
Molecular weight
37.70 kDa
pI
8.82
Protein length
Gene length
function
regulation of galacturonic acid utilization
product
transcriptional repressor of the pectin utilization operon ([wiki|LacI family])
essential
no
synonyms
kdgR

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1609 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,324,613  2,325,632
The protein
Protein family
[wiki|LacI family]
[wiki|Domains]
[wiki|HTH lacI-type domain] (aa 9-64) (according to UniProt)
Structure
[PDB|2HSG] (B. megaterium [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA], 26% identity) [pubmed|17500051]
[AF|P50844]
Expression and Regulation
Operons
genes
[gene|891A32A19D1353BA566FF121BBCA7B986D31D129|kdgR]-[gene|8A0BB2BE0AAAA7FF834A4549E8E2AF343FB10571|kdgK]-[gene|826BFCE6ED2113BB0510E798C6CDB05C4665E0E2|kdgA]-[gene|EB6F40F8651654E0AB09447C5AD670C35A59F261|kdgT]
description
[Pubmed|9846747]
regulation
induced by galacturonate ([protein|891A32A19D1353BA566FF121BBCA7B986D31D129|kdgR]) [Pubmed|9846747]
regulatory mechanism
[protein|891A32A19D1353BA566FF121BBCA7B986D31D129|kdgR]: repression, [Pubmed|9846747], in [regulon|protein:891A32A19D1353BA566FF121BBCA7B986D31D129|kdgR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|9846747], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|9846747], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|891A32A19D1353BA566FF121BBCA7B986D31D129|kdgR]→[gene|EB6F40F8651654E0AB09447C5AD670C35A59F261|kdgT]

2024-10-19 08:11:09

Jstuelk

86

a5bed599599ed10a0553e473cf3c537c32010d6c

3F117D89C62E073C1B4EEA2460C1BBFC9A05A5A3

Biological materials
Mutant
BKE22120 ([gene|891A32A19D1353BA566FF121BBCA7B986D31D129|kdgR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22120 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCAAGTGCTCCTGTATC,  downstream forward: _UP4_TAATCCTAGGTGCCCTCAAC
BKK22120 ([gene|891A32A19D1353BA566FF121BBCA7B986D31D129|kdgR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22120 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCAAGTGCTCCTGTATC,  downstream forward: _UP4_TAATCCTAGGTGCCCTCAAC
References
17322190,22900538,9846747,17500051

891A32A19D1353BA566FF121BBCA7B986D31D129

Page visits: 4515

Time of last update: 2024-11-08 12:53:41

Author of last update: Melvin.boenninger