ytpQ
168
unknown
locus
BSU_29830
Molecular weight
30.89 kDa
pI
5.3
function
maybe involved in iron homeostasis
product
unknown
essential
no
ec
null
synonyms
ytpQ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4848 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,053,364 3,054,173
Phenotypes of a mutant
derepression of the [protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur] and [protein|00BCAAE16576DC5426A652580C69A570FC7A1C2C|perR] regulons [Pubmed|21949854]
elevated oxidative protein damage upon exposure of the cells to methylglyoxal [Pubmed|21949854]
the ''[gene|2C6386E9A63F410558D168798D077DF91590F454|spx] [gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]'' doulbe mutant shows reduced growth in minimal medium and hypersensitivity to methylglyoxal [Pubmed|21949854]
The protein
Protein family
UPF0354 family (single member, according to UniProt)
Structure
[AF|O34496]
Expression and Regulation
Operons
genes
[gene|314D5C01B4BDDC3B122F6D4066647B143B2A6543|ytpP]-[gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]-[gene|EE559CD606562097F09DC627F431CA31129D7BC6|ytpR]
description
[Pubmed|21949854]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [Pubmed|21949854], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21949854], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-A437 (ytpQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/437 NBRP B. subtilis, Japan]
BKE29830 ([gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTCAAACCGATGTCCT, downstream forward: _UP4_AAGGATTAGAAAGGATTTTT
BKK29830 ([gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTCAAACCGATGTCCT, downstream forward: _UP4_AAGGATTAGAAAGGATTTTT
References
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Time of last update: 2024-12-21 04:20:57
Author of last update: Melvin.boenninger