yvgJ
168
lipoteichoic acid synthesis primase
locus
BSU_33360
Molecular weight
70.57 kDa
pI
5.31
function
biosynthesis of lipoteichoic acid
product
lipoteichoic acid synthesis primase
essential
no
synonyms
yvgJ, yvsF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1368 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,422,354 3,424,207
The protein
Protein family
[wiki|LTA synthase family] (according to UniProt)
Structure
[PDB|2W5Q] ([protein|418900B6DBDF3EF300C930B0C75E31B939F3CE00|ltaS] from S. aureus, corresponds to aa 215 ... 615 of [protein|880C655DC7149F6EDC21BD2CF8F9F2C9FBEB2CDB|yvgJ]) [pubmed|19168632]
[AF|O32206]
Modification
can be phosphorylated by [protein|23FF4A00C36EC1B7297F51A9EF3579B41F0B7EBA|prkC] in vitro [pubmed|30478337]
Paralogous protein(s)
[protein|CCD06F344E3C87E77C3D13883CE2B927F372A84E|yfnI], [protein|2B33F2F9C2FB0767B72A29D060037393C88ACEE5|yqgS], [protein|418900B6DBDF3EF300C930B0C75E31B939F3CE00|ltaS]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|880C655DC7149F6EDC21BD2CF8F9F2C9FBEB2CDB|yvgJ]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B065 (yvgJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1064 NBRP B. subtilis, Japan]
BKE33360 ([gene|880C655DC7149F6EDC21BD2CF8F9F2C9FBEB2CDB|yvgJ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATATGACTCCTCACG, downstream forward: _UP4_TGAAAAAATCCCTCTATCAA
BKK33360 ([gene|880C655DC7149F6EDC21BD2CF8F9F2C9FBEB2CDB|yvgJ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATATGACTCCTCACG, downstream forward: _UP4_TGAAAAAATCCCTCTATCAA
References
Reviews
Original Publications
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Time of last update: 2024-10-09 04:09:49
Author of last update: Melvin.boenninger